Cathepsin K anticorps (Middle Region)

N° du produit ABIN452891

L’anticorps anti-Cathepsin K Polyclonal Lapin est utilisé pour la détection de Cathepsin K dans des échantillons de Humain. Il a été validé pour WB et EIA.

Aperçu rapide pour Cathepsin K anticorps (Middle Region) (ABIN452891)

Antigène: Cathepsin K (CTSK)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Cathepsin K est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-Cathepsin K anticorps

Épitope: Middle Region

Specificité: This antibody detects Cathepsin K at Center, R222.

Réactivité croisée (Details): Species reactivity (tested):Human

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogène: KLH conjugated synthetic peptide selected from the Center region of human CTSK

Information d'application

Indications d'application: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Détails sur Cathepsin K

Antigène: Cathepsin K (CTSK)

Autre désignation: Cathepsin K

Sujet: The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.Synonyms: CTSK, CTSO, CTSO2, Cathepsin O, Cathepsin O2, Cathepsin X

Poids moléculaire: 36966 Da

ID gène: 1513

NCBI Accession: NP_000387

UniProt: P43235

Pathways: Activation of Innate immune Response, Toll-Like Receptors Cascades