COQ3 anticorps (Middle Region)
Aperçu rapide pour COQ3 anticorps (Middle Region) (ABIN453581)
Antigène
Voir toutes COQ3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- Middle Region
-
Specificité
- This antibody reacts to COQ3.
-
Purification
- Affinity chromatography on Protein A
-
Immunogène
- KLH conjugated synthetic peptide selected from the Center region of human COQ3
-
-
-
-
Indications d'application
-
ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 0.25 mg/mL
-
Buffer
- PBS with 0.09 % (W/V) sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- COQ3 (Coenzyme Q3, Methyltransferase (COQ3))
-
Autre désignation
- COQ3
-
Sujet
- Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. COQ3 is an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.Synonyms: 3, 4-dihydroxy-5-hexaprenylbenzoate methyltransferase, DHHB methyltransferase, DHHB-MTase, Dihydroxyhexaprenylbenzoate methyltransferase, mitochondrial Hexaprenyldihydroxybenzoate methyltransferase
-
ID gène
- 51805
-
NCBI Accession
- NP_059117
-
UniProt
- Q9NZJ6
-
Pathways
- Methionine Biosynthetic Process
Antigène
-