PSMA7 anticorps (Middle Region)

N° du produit ABIN453792

Cet anticorps anti-PSMA7 Polyclonal Lapin (ABIN453792) détecte spécifiquement PSMA7 dans WB et EIA. L’anticorps est réactif avec des échantillons de Humain et Souris.

Aperçu rapide pour PSMA7 anticorps (Middle Region) (ABIN453792)

Antigène: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMA7 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Détail du produit anti-PSMA7 anticorps

Épitope: Middle Region

Specificité: This antibody reacts to PSMA7.

Purification: Affinity chromatography on Protein A

Immunogène: KLH conjugated synthetic peptide selected from the Center region of human PSMA7

Information d'application

Indications d'application: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PSMA7

Antigène: PSMA7 (Proteasome Subunit alpha 7 (PSMA7))

Autre désignation: PSMA7

Sujet: The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMA7 is a member of the peptidase T1A family, that is a 20S core alpha subunit. This particular subunit has been shown to interact specifically with the hepatitis B virus X protein, a protein critical to viral replication. In addition, this subunit is involved in regulating hepatitis virus C internal ribosome entry site (IRES) activity, an activity essential for viral replication. This core alpha subunit is also involved in regulating the hypoxia-inducible factor-1alpha, a transcription factor important for cellular responses to oxygen tension.Synonyms: HSPC, Proteasome subunit RC6-1, Proteasome subunit XAPC7, Proteasome subunit alpha type-7

ID gène: 5688

NCBI Accession: NP_002783

UniProt: O14818

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA