Smith Antigen anticorps

N° du produit ABIN453884

L’anticorps anti-Smith Antigen Polyclonal Human est utilisé pour la détection de Smith Antigen dans des échantillons de Humain. Il a été validé pour ID et EIA.

Aperçu rapide pour Smith Antigen anticorps (ABIN453884)

Antigène: Smith Antigen

Reactivité: Humain

Hôte: Human

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Immunodiffusion (ID), Enzyme Immunoassay (EIA)

Détail du produit

Purification: Single donor human plasma is delipidized and defibrinated. An immunoglobulin fraction is then precipitated and collected.

Information d'application

Indications d'application: Immunodiffusion. ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Reconstitution: Restore with 2 mL deionized water

Buffer: 0.01 M Phosphate, 0.11 M Sodium chloride containing 0.02 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: Source material supplied to your facility has been tested for the detection of HIV antibody, Hepatitis B surface antigen, antibody to Hepatitis C, HIV 1 antigen(s), antibody to HTLV - I/II, and syphilis with FDA approved test kits. All units were found to be non- reactive/negative for these tests. Nevertheless, all products from human sources should be handled as potentially infectious.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détail du antigène

Antigène: Smith Antigen

Autre désignation: Sm / Smith Antigen

Sujet: The sm (Smith) is an autoantigen on a series of particles composed of RNA and protein. Unlike RNP, the sm antigen is resistant to RNase, but partially sensitive to trypsin. It is involved in the pathogenesis of Systemic lupus erythematosus (SLE). Antibodies to sm are found in 20-30 % of patients with SLE. This antibody recognizes cross-reactive epitopes on the B'/B and D polypeptides of Sm. It precipitates the small nuclear RNAs U1, U2, U4, U5, and U6 providing direct evidence that the Sm antigen resides on all these RNA-protein complexes.Synonyms: Human Autoantigens