SAA anticorps

N° du produit ABIN453893

L’anticorps Souris Monoclonal anti-SAA a été validé pour WB et EIA. Il convient pour détecter SAA dans des échantillons de Humain.

Aperçu rapide pour SAA anticorps (ABIN453893)

Antigène: SAA (Serum Amyloid A (SAA))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SAA est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 513

Détail du produit anti-SAA anticorps

Specificité: Reacts with natural and recombinant Human SAA. Does not show any cross-reaction with other Human Cytokines or Growth Factors tested such as IL1 beta, IL-8, MCAF, TGF beta and EGF.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein G.

Immunogène: Highly purified recombinant Human SAA. Remarks: Molecular Weight: 12 kDa

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western Blot: Use of this SSA antibody at a concentration of 0.1-0.5 μg will allowvisualization of 100 ng/lane of recombinant Human SAA.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with Double distillated water to adjust the final concentration to 1.0 mg/mL.

Buffer: 0.01 M PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: This product is photosensitive and should be protected from light

Stock: 4 °C

Stockage commentaire: Store the antibody at 2 - 8 °C. DO NOT FREEZE!

Détails sur SAA

Antigène: SAA (Serum Amyloid A (SAA))

Autre désignation: Serum Amyloid A Protein (SAA)

Sujet: The Serum Amyloid A (SAA) family comprises a number of differentially expressed lipoproteins, acute phase SAA1 and SAA2, the former being a major component in plasma, and constitutive SAA's (C-SAAs). Although the liver is the primary site of synthesis of both SAA types, extrhepatic production has been reported. The in vivo concentrations increase by as much as 1000 fold during inflammation. Several studies have expressed it's importance in the diagnosis and monitoring of various diseases. Pathological SAA values are often detected in association with normal CRP concentrations. SAA rises earlier and more sharply than CRP. SAA enhances the binding of HDL's to macrophages and thus helps the delivery of lipid to sites of injury for use in tissue repair. It is thus thought to be an integral part of the disease process. In addition, recent experiments suggest that SAA may play a "houekeeping" role in normal human tissues. Elevated levels of SAA over time predispose secondary amyloidosis, extracellular accumulation of amyloid fibrils, derived from a circulating precursor, in various tissues and organs. The most common form of amyloidosis occurs secondary to chronic inflammatory disease, particularly rheumatoid artheritis.Synonyms: SAA1, SAA2

ID gène: 6288

NCBI Accession: NP_000322

UniProt: P02735