CCL7 anticorps (Biotin)

N° du produit ABIN453919

Cet anticorps Souris Monoclonal détecte spécifiquement CCL7 dans EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour CCL7 anticorps (Biotin) (ABIN453919)

Antigène: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL7 est conjugé à/à la Biotin

Application: Enzyme Immunoassay (EIA)

Clone: 113

Détail du produit anti-CCL7 anticorps (Biotin)

Specificité: Reactive with natural and recombinant human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Affinity Chromatography on Protein G.

Immunogène: Purified Recombinant Human Monocyte Chemotactic Protein-3 (MCP-3).

Isotype: IgG1

Information d'application

Indications d'application: ELISA: This MCP3 antibody Biotin-conjugated can be used as a Tracer/Detection Antibodyin Sandwich ELISA applications for human MCP-3 detection in combination with a Captureantibody (Cat#DM2039)Suggested Capture Coating Dose: 3 μg/wellSubstrate: TMB
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 0.01 M PBS, pH 7.0 ± 0.1, 0.1 % Proclin-300, 1 % Gelatin

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody at 2 - 8 °C. DO NOT FREEZE!

Détails sur CCL7

Antigène: CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))

Autre désignation: MCP3 / CCL7

Sujet: Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78 % sequence homology with MCP-1 and 58 % sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1α to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7

ID gène: 6354

NCBI Accession: NP_006264

UniProt: P80098