CCL7 anticorps (HRP)
Aperçu rapide pour CCL7 anticorps (HRP) (ABIN453920)
Antigène
Voir toutes CCL7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- Reactive with natural and recombinant human MCP-3. Does not show any cross reaction with other Human Cytokines or growth factors tested such as IL1 beta, IL-8, MCAF, SAA and EGF
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Réactivité croisée (Details)
- Species reactivity (tested):Human.
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Purification
- Affinity Chromatography on Protein G.
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Immunogène
- Purified Recombinant Human Monocyte Chemotactic Protein-3 (MCP-3).
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Isotype
- IgG1
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Indications d'application
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ELISA: This MCP3 antibody HRP-conjugated can be used as a Tracer/Detection Antibody inSandwich ELISA applications for human MCP-3 detection in combination with a Captureantibody (Cat#DM2039)Suggested Capture Coating Dose: 3 μg/wellSubstrate: TMB
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.01 M PBS, pH 7.0 ± 0.1 in 50 % Glycerol and 0.01 % Thimerosal as a bacteriostat
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody at 2 - 8 °C. DO NOT FREEZE!
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- CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
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Autre désignation
- MCP3 / CCL7
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Sujet
- Macrophage/monocyte chemotactic protein-3 (MCP-3), like other two closely related chemokines (MCP1 and MCP-2), is chemotactic to monocytes, but not to neutrophils. MCP-3 showed 78 % sequence homology with MCP-1 and 58 % sequence homology with MCP-2. The primary receptor for MCP-3 is D6. MCP-3 also competes with MCP-1 to bind to CCR10, and competes with Rantes and MIP-1α to bind to CCR1. MCP-3 stimulates macrophage to secrete proteases. A variety of cancer cell lines express MCP-3, suggesting a role in tumor invasion and metastasia.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7
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ID gène
- 6354
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NCBI Accession
- NP_006264
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UniProt
- P80098
Antigène
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