SELPLG anticorps

N° du produit ABIN457437

Détail du produit anti-SELPLG anticorps

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SELPLG est non-conjugé

Application: Flow Cytometry (FACS)

Specificité: The antibody TC2 reacts with an extracellular epitope of CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes, it is also expressed on a subpopulation of B lymphocytes and CD34⁺ bone marrow cells.

Réactivité croisée (Details): Human

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

Immunogène: Human thymocytes

Clone: TC2

Isotype: IgG1

Information d'application

Indications d'application: Flow cytometry: Recommended dilution: 1.5 - 2.5 μg/mL, positive control: human peripheral blood.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur SELPLG

Antigène: SELPLG (Selectin P Ligand (SELPLG))

Autre désignation: CD162 (SELPLG Produits)

Synonymes: anticorps CD162, anticorps CLA, anticorps PSGL-1, anticorps PSGL1, anticorps SELPLG, anticorps SELPG, anticorps Psgl-1, anticorps Psgl1, anticorps Selp1, anticorps Selpl, anticorps selectin P ligand, anticorps selectin, platelet (p-selectin) ligand, anticorps clasper, anticorps SELPLG, anticorps Selplg, anticorps cla

Sujet: Selectin P ligand,CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.,PSGL-1, Selectin P ligand, SELPLG, CLA

ID gène: 6404

UniProt: Q14242