SELPLG anticorps
Aperçu rapide pour SELPLG anticorps (ABIN457437)
Antigène
Voir toutes SELPLG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Anti-Hu CD162 Purified
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Réactivité croisée (Details)
- Human
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Attributs du produit
- The antibody TC2 reacts with an extracellular epitope of CD162, a 220 kDa type I integral membrane protein expressed as disulfide-linked homodimer (sialomucin family). CD162 is present on the most peripheral blood T lymphocytes, monocytes, granulocytes, it is also expressed on a subpopulation of B lymphocytes and CD34+ bone marrow cells.
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Purification
- Purified by protein-A affinity chromatography.
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Pureté
- > 95 % (by SDS-PAGE)
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Immunogène
- Human thymocytes
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Isotype
- IgG1
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Indications d'application
- Flow cytometry: Recommended dilution: 1.5 - 2.5 μg/mL, positive control: human peripheral blood.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- SELPLG (Selectin P Ligand (SELPLG))
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Autre désignation
- CD162
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Sujet
- Selectin P ligand,CD162 (P-selectin glycoprotein ligand-1, PSGL-1) is a sialomucin constitutively expressed as a disulfide-linked homodimer of two 120 kDa subunits on the surface of circulating leukocytes. CD162 serves as a ligand for P- E- and L-selectin, with the highest affinity for P-selectin. It is thus involved in leukocyte rolling at the endothelial surfaces, prerequisite for firm leukocyte adhesion and subsequent transendothelial migration. CD162 also mediates leukocyte-platelet adhesion and interleukocyte contacts. Whereas serving as an adhession molecule on mature leukocytes, CD162 is a potent negative regulator of human hematopoietic progenitors.,PSGL-1, Selectin P ligand, SELPLG, CLA
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ID gène
- 6404
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UniProt
- Q14242
Antigène
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