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beta-Thromboglobulin anticorps

L’anticorps Lapin Polyclonal anti-beta-Thromboglobulin a été validé pour ELISA, ID et Neph. Il convient pour détecter beta-Thromboglobulin dans des échantillons de Humain.
N° du produit ABIN458153

Aperçu rapide pour beta-Thromboglobulin anticorps (ABIN458153)

Antigène

Voir toutes beta-Thromboglobulin (beta-TG) Anticorps
beta-Thromboglobulin (beta-TG)

Reactivité

  • 5
  • 5
  • 4
  • 1
Humain

Hôte

  • 12
  • 3
Lapin

Clonalité

  • 12
  • 3
Polyclonal

Conjugué

  • 9
  • 3
  • 3
Cet anticorp beta-Thromboglobulin est non-conjugé

Application

  • 15
  • 15
  • 9
  • 6
  • 6
  • 3
ELISA, Immunodiffusion (ID), Nephelometry (Neph)
  • Specificité

    Inter-species cross-reactivity is a normal feature of antibodies to plasma proteins, since homologous proteins of different species frequently share antigenic determinants. of this antiserum has not been tested in detail.

    Attributs du produit

    Precipitating polyclonal rabbit antiserum to human beta-thromboglobulin

    Purification

    Adsorption: Immunoaffinity adsorbed using insolubilized antigens as required, to eliminate antibodies reacting with other human serum proteins. The use of insolubilized adsorption antigens prevents the presence of excess adsorbent protein or immune complexes in the antiserum.

    Immunogène

    Beta-thromboglobulin is a platelet specific protein. In normal plasma mean concentrations of 30 ng/ml have been found. Highly purified beta-thromboglobulin has been isolated from platelets and is used for the immunization. Freund’s complete adjuvant is used in the first step of the immunization procedure.

    Isotype

    IgG
  • Indications d'application

    In plasma the beta-thromboglobulin can only be assayed in more sensitive methods as ELISA, because of the low concentration of the antigen: in electroimmunodiffusion (Laurell), immunonephelometry, solid phase assays and as catching or detection antibody in ELISA. Measurements of beta-thromboglobulin is of significance for the diagnosis of platelet disorders involving platelet alpha granules and to demonstrate increased platelet secretions in vivo.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Concentration

    Total protein and IgG concentrations in the antiserum are comparable to those of normal pooled rabbit serum. No foreign proteins added. Antibody titre: The amount of beta-thromboglobulin precipitated by 1 ml antiserum is approximately 0.2 mg.

    Buffer

    Delipidated, heat inactivated, lyophilized, stable whole serum.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    The lyophilized antiserum is shipped at ambient temperature and may be stored at +4°C, prolonged storage at or below -20°C. Reconstitute the lyophilized antiserum by adding 1 ml sterile distilled water. Dilutions may be prepared by adding phosphate buffered saline (PBS, pH 7.2). Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation. It will not affect the performance of the antiserum. Diluted antiserum should be stored at +4°C, not ref rozen, and preferably used the same day.
  • Antigène

    beta-Thromboglobulin (beta-TG)

    Autre désignation

    beta-Thromboglobulin

    Sujet

    The defined antibody specificity is restricted to beta-thromboglobulin as tested at the level of sensitivity of immunoprecipitation techniques. A single precipitin line is obtained in bid-dimensional electrophoresis against normal plasma and platelet concentrate lysate, which shows a reaction of identity with precipitated purified beta-thromboglobulin. The antiserum does not react with any other protein component of human serum or plasma
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