AGPAT2 anticorps

N° du produit ABIN4620346

Détail du produit anti-AGPAT2 anticorps

Antigène: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp AGPAT2 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: This antibody detects Lysophosphatidic Acid Acetyltransferase beta.

Purification: Purified

Immunogène: Synthetic peptide derived from the LPAAT-beta protein.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 5-10 μg/mL. Enzyme Immunoassay. Positive Control: Human Brain Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Ship on dry ice. Store (in aliquots) at -20 °C only.

Détails sur AGPAT2

Antigène: AGPAT2 (1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2))

Autre désignation: AGPAT2 (AGPAT2 Produits)

Synonymes: anticorps AGPAT2, anticorps zgc:153984, anticorps 1-agpat2, anticorps bscl, anticorps bscl1, anticorps lpaab, anticorps lpaat-beta, anticorps 1-AGPAT2, anticorps BSCL, anticorps BSCL1, anticorps LPAAB, anticorps LPAAT-beta, anticorps 2510002J07Rik, anticorps AV000834, anticorps 1-acylglycerol-3-phosphate O-acyltransferase 2, anticorps 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta), anticorps AGPAT2, anticorps agpat2, anticorps Agpat2

Sujet: Lysophospholipid Acyltransferases (LPLATs) catalyse the addition of fatty acyl moieties to the glycerol backbone of lysophospholipids . In addition to playing a crutial role in the synthesis of structural membrane components the LPLATs are also implicated in cellular signalling responses for cytokines, growth factors and other agonists. Cellular signalling through the interleukin 1 receptor in human mesangial cells and EL-4 cells proceeds by the activation of lysophosphatidic acid acyltransferase (LPAAT). Activation of LPAAT by interleukin 1 results in the generation of unsaturated phosphatidic acid species, that are crucial to the generation of diacylglycerol and interleukin 1 signalling. LPLATs are also involved in signalling for increased interleukin 2 synthesis through the T cell antigen receptor. Activation of T-cells via anti-CD3 stimulation has been shown to increase incorporation of polyunsaturated fatty acids into phosphatidylcholine via lysophosphatidylcholine acyltransferase. Activation of this enzyme is essential for the sustained activation and translocation of protein kinase C.Synonyms: 1-AGP acyltransferase 2, 1-acyl-sn-glycerol-3-phosphate acyltransferase beta, 1-acylglycerol-3-phosphate O-acyltransferase 2, LPAAT-beta, Lysophosphatidic acid acyltransferase beta

ID gène: 10555

NCBI Accession: NP_001012745

UniProt: O15120