Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13) anticorps

N° du produit ABIN4620374

Détail du produit

Antigène: Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Western Blotting (WB)

Specificité: This antibody detects P2Y13.

Purification: Affinity chromatography

Immunogène: Synthetic peptide derived from human GPCR94

Information d'application

Indications d'application: Western blot (1: 400 starting dilution).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the product (in aliquots) at -20 °C. Can be shipped at 2 - 8 °C.

Détail du antigène

Antigène: Purinergic Receptor P2Y, G-Protein Coupled, 13 (P2RY13)

Autre désignation: P2Y13 / P2YR13 (P2RY13 Produits)

Synonymes: anticorps MGC80556, anticorps MGC108160, anticorps 2010001L06Rik, anticorps GPCR1, anticorps GPR94, anticorps Gpr86, anticorps P2Y13, anticorps P2yr13, anticorps SP174, anticorps GPR86, anticorps P2y13, anticorps purinergic receptor P2Y, G-protein coupled, 13 L homeolog, anticorps purinergic receptor P2Y, G-protein coupled, 13, anticorps purinergic receptor P2Y13, anticorps purinergic receptor P2Y, G-protein coupled 13, anticorps p2ry13.L, anticorps p2ry13, anticorps P2RY13, anticorps P2ry13

Sujet: Receptor for ADP. Coupled to G(i)-proteins. May play a role in hematopoiesis and the immune system. Strong expression in spleen and adult brain. Lower expression in placenta, lung, liver, spinal cord, thymus, small intestine, uterus, stomach, testis, fetal brain, and adrenal gland. Not detected in pancreas, heart, kidney, skeletal muscle, ovary or fetal aorta. Clearly detected in lymph node and bone marrow, weakly detected in peripheral blood mononuclear cells (PBMC) and in peripheral blood leukocytes (PBL), but not detected in polymorphonuclear cells (PMN). In the brain, detected in all brain regions examined. Stimulation by ADP in stably transfected CHO cells resulted in inhibition of adenylyl cyclase and the phosphorylation of the MAP kinases MAPK3 and MAPK1 in a pertussis toxin-sensitive way. Inhibition of adenylyl cyclase and phosphorylation of the MAP kinases are transduction mechanisms that involve G(i) proteins.Synonyms: FKSG77, G-protein coupled receptor 86, G-protein coupled receptor 94, GPR86, GPR94, P2Y purinoceptor 13, Purinergic receptor

ID gène: 53829

NCBI Accession: NP_795713

UniProt: Q9BPV8

Pathways: cAMP Metabolic Process