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PTCHD2 anticorps (Middle Region)

PTCHD2 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN4620591
  • Antigène Voir toutes PTCHD2 Anticorps
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Épitope
    • 15
    • 9
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivité
    • 40
    • 7
    • 6
    • 4
    • 4
    • 4
    • 4
    Humain, Souris, Rat
    Hôte
    • 40
    Lapin
    Clonalité
    • 40
    Polyclonal
    Conjugué
    • 11
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp PTCHD2 est non-conjugé
    Application
    • 36
    • 19
    • 13
    • 13
    • 8
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Réactivité croisée (Details)
    Species reactivity (tested):Human, Mouse, Rat
    Purification
    Affinity chromatography purified via peptide column
    Immunogène
    19 amino acid synthetic peptide from near the center of human PTCHD2
    Isotype
    IgG
    Top Product
    Discover our top product PTCHD2 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % Sodium Azide as preservative
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène
    PTCHD2 (Patched Domain Containing 2 (PTCHD2))
    Autre désignation
    PTCHD2 (PTCHD2 Produits)
    Synonymes
    anticorps DISP3, anticorps G630052C06Rik, anticorps RNDEu-2, anticorps RGD1305820, anticorps dispatched RND transporter family member 3, anticorps patched domain-containing protein 2, anticorps si:dkey-32e23.6, anticorps DISP3, anticorps LOC100082708, anticorps si:dkey-32e23.6, anticorps disp3, anticorps Disp3
    Sujet
    PTCHD2, also known as DISP3, is the third of three known homologs of the D. melanogaster protein Dispatched. It is a multi-transmembrane protein containing two PTCH/DISP domains and is thought to be involved in the release of lipid-anchored secreted proteins. Like DISP1 and DISP2, DISP3 has been implicated in signaling pathways during embryogenesis, tissue regeneration, and carcinogenesis. It is highly expressed in Purkinje cells, hippocampal neurons, and retinal ganglion cells. Recently, it has been shown that PTCHD2 localizes within the endoplasmic reticulum and colocalizes with cholesterol, and given that its expression is regulated by thyroid hormone (T3), it has been suggested that DISP3 may be a link between thyroid hormone and cholesterol metabolism.Synonyms: DISP3, KIAA1337, Patched domain-containing protein 2, Protein dispatched homolog 3
    ID gène
    57540
    UniProt
    Q9P2K9
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