NCOA3 anticorps (AA 188-198)

N° du produit ABIN462508

Cet anticorps Chèvre Polyclonal détecte spécifiquement NCOA3 dans IHC et IHC (p). Il présente une réactivité envers Humain, Boeuf (Vache), Chien, Porc, Singe, Roussette (Chauve-souris) et Hamster.

Aperçu rapide pour NCOA3 anticorps (AA 188-198) (ABIN462508)

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Reactivité: Humain, Boeuf (Vache), Chien, Porc, Singe, Roussette (Chauve-souris), Hamster

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp NCOA3 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-NCOA3 anticorps

Épitope: AA 188-198

Marque: IHC-plus™

Specificité: Human NCOA3. This antibody is expected to recognise both reported isoforms (NP_006525.2, NP_858045.1)

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Hamster, Elephant, Panda, Dog, Bovine, Bat, Pig (100%) Mouse, Rat, Horse, Rabbit (91%) Opossum, Turkey, Platypus, Lizard (82%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-TNETQRQKSHT from an internal region of human NCOA3 (NP_006525.2, NP_858045.1). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Hamster, Elephant, Panda, Dog, Bovine, Bat, Pig (100%), Mouse, Rat, Horse, Rabbit (91%), Opossum, Turkey, Platypus, Lizard (82%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (3.75 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur NCOA3

Antigène: NCOA3 (Nuclear Receptor Coactivator 3 (NCOA3))

Autre désignation: NCOA3 / SRC-3 / AIB1

Sujet: Name/Gene ID: NCOA3

Synonyms: NCOA3, ACTR, AIB1, BHLHe42, CAGH16, CBP-interacting protein, CTG26, AIB-1, P/CIP, TNRC14, TRAM-1, Nuclear receptor coactivator 3, PCIP, RAC-3, SRC3, TNRC16, KAT13B, NCoA-3, SRC-3

ID gène: 8202

NCBI Accession: NP_006525, NP_858045

UniProt: Q9Y6Q9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Lipid Metabolism by PPARalpha