PKD1 anticorps (AA 4289-4300)

N° du produit ABIN462530

L’anticorps anti-PKD1 Polyclonal Chèvre est utilisé pour la détection de PKD1 dans des échantillons de Humain. Il a été validé pour IHC et IHC (p).

Aperçu rapide pour PKD1 anticorps (AA 4289-4300) (ABIN462530)

Antigène: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp PKD1 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-PKD1 anticorps

Épitope: AA 4289-4300

Specificité: Human PKD1. This antibody is expected to recognize both reported isoforms (NP_001009944.1 and NP_000287.2).

Homologie: Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%) Marmoset, Panda, Cat, Dog, Horse (83%).

Purification: Immunoaffinity purified

Immunogène: Synthetic peptide C-RTPLRAKNKVHP from the C-terminus of human PKD1 (NP_001009944.1, NP_000287.2). Percent identity by BLAST analysis: Human, Gorilla, Gibbon (100%), Marmoset, Panda, Cat, Dog, Horse (83%).

Type of Immunogen: Synthetic peptide

Information d'application

Indications d'application: Approved: IHC, IHC-P (3.75 μg/mL)

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 3.75 μg/mL.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Tris-buffered saline,  pH 7.3, 0.5 % BSA, 0.02 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Minimize freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur PKD1

Antigène: PKD1 (Polycystic Kidney Disease 1 (Autosomal Dominant) (PKD1))

Autre désignation: PKD1 / Polycystin

Sujet: Name/Gene ID: PKD1

Synonyms: PKD1, PBP, Polycystin, TRPP1, Pc-1, Polycystin 1, Polycystin-1

ID gène: 5310

NCBI Accession: NP_001009944, NP_000287

UniProt: P98161

Pathways: Myometrial Relaxation and Contraction, Maintenance of Protein Location