Desmoglein 1/2 anticorps (C-Term)

N° du produit ABIN470806

Détail du produit anti-Desmoglein 1/2 anticorps

Antigène: Desmoglein 1/2 (DSG1/2)

Épitope: C-Term

Reactivité: Boeuf (Vache), Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Desmoglein 1/2 est non-conjugé

Application: Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB), Immunofluorescence (IF)

Specificité: Species (tested so far) Human, bovine, rat, mouse. Recognizes desmoglein 1 + 2 (desmosome-specific cadherins) in desmosome-bearing cells, does not react with cells containing plaque-bearing junctions of non-desmosomal type. Tumors specifically detected: all epithelium-derived tumors, notably carcinomas, and meningiomas. Polypeptide reacting: Mr 165000 Desmoglein, 'band 3' polypeptide of the desmosomal complex. Epitope recognized has been localized at the repeating unit domain ('RUD') of the cytoplasmic C-terminal part of the polypeptide. Reactivities on Cultured Cell Lines (tested so far): A-431, MCF-7, TR-146, PLC and various other human epithelial cell lines, bovine BMGE+H, BMGE-H, MDBK.

Purification: Protein A purified

Immunogène: Band 3 polypeptide of isolated desmosomes from bovine muzzle epidermis.

Type of Immunogen: Protein

Isotype: IgG1

Information d'application

Indications d'application: Approved: IF, IHC, IHC-Fr, IHC-P, WB

Usage: Suitable for use in Immunohistochemistry (frozen sections, paraffin-embedded tissue after microwave treatment), Western Blot, Cryo, Paraffin (Microwave), Immunofluorescence microscopy. Immunohistochemistry: 1:10 with PBS,  pH 7.4, Incubation Time 1 h at RT, extended with paraffin.

Commentaires:

Target Species of Antibody: Bovine

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: deionized water

Concentration: Lot specific

Buffer: Lyophilized.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Détails sur Desmoglein 1/2

Antigène: Desmoglein 1/2 (DSG1/2)

Autre désignation: Desmoglein 1/2 (DSG1/DSG2) (DSG1/2 Produits)

Synonymes: anticorps DSG1, anticorps desmoglein 1, anticorps DSG1

Sujet: This antibody detects: DSG1+2 / Desmoglein 1+2