Insulin C-Peptide anticorps

N° du produit ABIN472131

Détail du produit anti-Insulin C-Peptide anticorps

Antigène: Insulin C-Peptide

Reactivité: Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Insulin C-Peptide est non-conjugé

Application: ELISA

Specificité: Recognizes rat C-peptide. C-peptide is a 31 amino acid peptide released when proinsulin is split into insulin and C-peptide. In rats, two isoforms of proinsulin exists, the difference is two amino acid residues in the C-peptide, termed C-peptide I and C-peptide II. Proinsulin is split when it is released from the pancreas into the blood in response to a rise in serum glucose levels. C-peptide function is not fully understood, it binds to cell membranes which leads to increased intracellular Ca2+ concentration and subsequent stimulation of N+, K+-ATPase and endothelial nitric oxide synthase activities. C-peptide also functions in repair of the muscular layer of arteries. Recognizes rat and mouse C-peptide I and rat C-peptide II with equal affinity. Reacts weakly with mouse C-peptide II. It does not recognize rat proinsulin. May be used as a capture antibody in ELISA assays for rat or mouse C-peptides I or II.

Purification: Affinity purified

Immunogène: Fragments of rat C-peptide conjugated to a carrier protein.

Clone: CC34

Isotype: IgG1

Information d'application

Indications d'application: Approved: ELISA, SwELISA

Usage: ELISA: This product may be used in an indirect ELISA or as a capture antibody in a sandwich ELISA ?to detect rat C-peptide I together with LS-C58408 as a detection reagent. These sandwich ELISA combinations are not suitable for the detection of mouse C-peptide I or II.

Commentaires:

Target Species of Antibody: Rat

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Short term: -20°C
Long term: -20°C.

Détails sur Insulin C-Peptide

Antigène: Insulin C-Peptide

Abstract: Insulin C-Peptide Produits

Synonymes: anticorps IDDM2, anticorps ILPR, anticorps IRDN, anticorps MODY10, anticorps insulin, anticorps INS