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Keratin 5/14 anticorps (C-Term)

Cet anticorps anti-Keratin 5/14 est un anticorps Souris Monoclonal détectant Keratin 5/14 dans IHC, IF, ICC et IHC (fro). Adapté pour Humain.
N° du produit ABIN472479

Aperçu rapide pour Keratin 5/14 anticorps (C-Term) (ABIN472479)

Antigène

Keratin 5/14 (KRT5/14)

Reactivité

Humain

Hôte

  • 1
Souris

Clonalité

  • 1
Monoclonal

Conjugué

  • 1
Cet anticorp Keratin 5/14 est non-conjugé

Application

Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Épitope

    C-Term

    Specificité

    This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as to 50kD cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58kD protein, which is closely related to cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis and rectal-anal region. Cytokeratin 5 can be useful in the distinction of mesotheliomas from most adenocarcinomas. Cytokeratin 14 belongs to the type A (acidic) subfamily of low MW cytokeratins and exists in combination with cytokeratin 15. This antibody can be useful to distinguish stratified epithelial cells from simple epithelial cells. Species cross-reactivity: This antibody is reactive against human.

    Purification

    Purified

    Immunogène

    Prokaryotic recombinant protein corresponding to 103 amino acid portion of C-terminal region of the human cytokeratin 5 molecule. LLLLL: Synthetic peptide of the extreme c-terminal of human keratin-14.

    Type of Immunogen: Synthetic peptide

    Isotype

    IgG1, IgG3
  • Indications d'application

    Approved: ICC, IF, IHC, IHC-Fr

    Usage: Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry (Fr) and Immunocytochemistry. Positive control: Skin.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS,  pH 7.2, 0.08 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Do not freeze. Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Freezing will result in a substantial loss of activity.
  • Antigène

    Keratin 5/14 (KRT5/14)

    Autre désignation

    Cytokeratin 5+14

    Sujet

    This antibody detects: Cytokeratin 5+14
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