Keratin 5/14 anticorps (C-Term)
Aperçu rapide pour Keratin 5/14 anticorps (C-Term) (ABIN472479)
Antigène
Reactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Specificité
- This antibody cocktail reacts with cytokeratin 5 intermediate filament protein as well as to 50kD cytokeratin protein designated cytokeratin 14. Basal cells of human epidermis express acidic cytokeratin 14 and basic cytokeratin 5. Cytokeratin 5 is a 58kD protein, which is closely related to cytokeratin 6. Cytokeratin 5 and 6 are expressed in basal cell epithelioma, basal cells of prostate, urothelium, vagina, squamous cell carcinomas of skin, tongue, epiglottis and rectal-anal region. Cytokeratin 5 can be useful in the distinction of mesotheliomas from most adenocarcinomas. Cytokeratin 14 belongs to the type A (acidic) subfamily of low MW cytokeratins and exists in combination with cytokeratin 15. This antibody can be useful to distinguish stratified epithelial cells from simple epithelial cells. Species cross-reactivity: This antibody is reactive against human.
-
Purification
- Purified
-
Immunogène
-
Prokaryotic recombinant protein corresponding to 103 amino acid portion of C-terminal region of the human cytokeratin 5 molecule. LLLLL: Synthetic peptide of the extreme c-terminal of human keratin-14.
Type of Immunogen: Synthetic peptide -
Isotype
- IgG1, IgG3
-
-
-
-
Indications d'application
-
Approved: ICC, IF, IHC, IHC-Fr
Usage: Suitable for use in Immunofluorescence, Western Blot and Immunohistochemistry (Fr) and Immunocytochemistry. Positive control: Skin. -
Commentaires
-
Target Species of Antibody: Human
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- Lot specific
-
Buffer
- PBS, pH 7.2, 0.08 % sodium azide.
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C
-
Stockage commentaire
- Do not freeze. Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Freezing will result in a substantial loss of activity.
-
-
- Keratin 5/14 (KRT5/14)
-
Autre désignation
- Cytokeratin 5+14
-
Sujet
- This antibody detects: Cytokeratin 5+14
Antigène
-