CCAR1 anticorps (Internal Region)
Aperçu rapide pour CCAR1 anticorps (Internal Region) (ABIN487983)
Antigène
Voir toutes CCAR1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Internal Region
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Specificité
- This antibody reacts to CCAR1.
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Réactivité croisée (Details)
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Species reactivity (expected):Canine, Bovine, Porcine.
Species reactivity (tested):Mouse, Rat. -
Purification
- Affinity chromatography
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Immunogène
- Peptide with sequence RYCKERPSKDKE, from the internal region (near C-Terminus) of the protein sequence according to NP_060707.2.
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Indications d'application
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Peptide ELISA: 1/16000. Western blot: Approx 120 kDa band observed in Mouse and Rat Skeletal Muscle lysates(calculated MW of 130 kDa according to Mouse NP_080477.1 and Rat NP_001102005.1). Recommended concentration: 1 - 3 μg/mL. An additional band of unknown identity was also consistently observed at 30 kDa. Thisband was successfully blocked by incubation with the immunizing peptide.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 0.5 mg/mL
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Buffer
- Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- CCAR1 (Cell Division Cycle and Apoptosis Regulator 1 (CCAR1))
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Autre désignation
- CCAR1
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Sujet
- DIS is thought to be involved in apoptosis signaling in the presence of the reinoid CD437. Apoptosis induction involves sequestration of 14-3-3 protein(s) and mediated altered expression of multiple cell cycle regulatory genes including MYC, CCNB1 and CDKN1A. Therefore DIS would have a role in cell cycle progression and/or cell proliferation.Synonyms: CARP1, Cell cycle and apoptosis regulatory protein 1, Cell division cycle and apoptosis regulator protein 1, DIS, Death inducer with SAP domain
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ID gène
- 55749
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NCBI Accession
- NP_060707
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UniProt
- Q8IX12
Antigène
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