Sorting Nexin 1 anticorps (Internal Region)

N° du produit ABIN487988

L’anticorps anti-Sorting Nexin 1 Polyclonal Chèvre est utilisé pour la détection de Sorting Nexin 1 dans des échantillons de Humain, Rat, Souris, Boeuf (Vache) et Chien. Il a été validé pour WB, IF, IHC (p) et EIA.

Aperçu rapide pour Sorting Nexin 1 anticorps (Internal Region) (ABIN487988)

Antigène: Sorting Nexin 1 (SNX1)

Reactivité: Humain, Rat, Souris, Boeuf (Vache), Chien

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp Sorting Nexin 1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-Sorting Nexin 1 anticorps

Épitope: Internal Region

Specificité: This antibody is expected to recognize isoform a and c (NP_003090.2, NP_690039.1.

Réactivité croisée (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogène: Peptide with sequence C-TNSSKPQPTYEELE, from the internal region of the protein sequence according to NP_003090.2, NP_690039.1.

Information d'application

Indications d'application: Peptide ELISA: 1/64000. Western blot: Approx 75 kDa band observed in Human lysates of cell line HeLa (calculatedMW of 59.5 kDa according to NP_003090.2). The observed molecular weight corresponds toearlier findings with different antibodies from other commercial sources. Recommended concentration: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Détails sur Sorting Nexin 1

Antigène: Sorting Nexin 1 (SNX1)

Autre désignation: Sorting Nexin-1 (SNX1)

Sujet: Sorting nexin 1 is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. This gene results in three transcript variants encoding distinct isoforms.

ID gène: 6642

NCBI Accession: NP_003090

UniProt: Q13596