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MORF4L1 anticorps (N-Term)

L’anticorps Chèvre Polyclonal anti-MORF4L1 a été validé pour WB, IHC (p) et EIA. Il convient pour détecter MORF4L1 dans des échantillons de Humain, Souris, Rat, Boeuf (Vache) et Chien.
N° du produit ABIN487997

Aperçu rapide pour MORF4L1 anticorps (N-Term) (ABIN487997)

Antigène

Voir toutes MORF4L1 Anticorps
MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

Reactivité

  • 43
  • 43
  • 23
  • 9
  • 9
  • 8
  • 8
  • 8
  • 7
  • 6
  • 3
  • 3
  • 2
  • 1
  • 1
Humain, Souris, Rat, Boeuf (Vache), Chien

Hôte

  • 54
  • 3
  • 2
Chèvre

Clonalité

  • 56
  • 3
Polyclonal

Conjugué

  • 30
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp MORF4L1 est non-conjugé

Application

  • 43
  • 15
  • 14
  • 14
  • 12
  • 6
  • 6
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • Épitope

    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    Séquence

    APKQDPKPKF QEG-C

    Specificité

    This antibody recognizes MRG15 and is expected to recognise Isoform 1 (NP_006782.1) and Isoform 2 (NP_996670.1).

    Réactivité croisée (Details)

    Species reactivity (expected):Mouse, Rat, Porcine, Bovine.
    Species reactivity (tested):Human.

    Purification

    Affinity Chromatography

    Immunogène

    Syntehtic peptide from the N-Terminus of Human MORF4L1 (NP_006782.1, NP_996670.1) . Genename: MORF4L1
  • Indications d'application

    Peptide ELISA: 1/64000. Western blot: Preliminary experiments gave an approx 40 kDa band in Human Liver lysatesand an approx 100 kDa band in Human Heart lysates at 1 μg/mL. Please note that currentlywe cannot find an explanation in the literature for the bands we observe given thecalculated size of 37.0 kDda according to NP_006782.1. Immunohistochemistry on paraffin sections: Human Uterus shows nuclear staining in theepithelial cells of the endometrial glands. Recommended concentration: 2 - 4 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.5 mg/mL

    Buffer

    Tris saline, pH ~7.3, 0.02 % Sodium Azide, 0.5 % BSA

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Antigène

    MORF4L1 (Mortality Factor 4 Like 1 (MORF4L1))

    Autre désignation

    MRG15

    Sujet

    MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.Synonyms: FWP006, HSPC008, HSPC061, MORF-related gene 15 protein, MORF4L1, MRG15, MSL3-1 protein, Mortality factor 4-like protein 1, PP368, Transcription factor-like protein MRG15

    Poids moléculaire

    37.2 kDa (Mouse NP_077751.1).

    ID gène

    10933

    NCBI Accession

    NP_006782

    UniProt

    Q9UBU8

    Pathways

    Chromatin Binding
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