CCR4 anticorps (C-Term)

N° du produit ABIN488046

Détail du produit anti-CCR4 anticorps

Antigène: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR4 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Recognizes C-C Chemokine Receptor 4 (CCR4/CD194).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide – KLH conjugated. Epitope: C-terminal domain of Human.

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.

Détails sur CCR4

Antigène: CCR4 (Chemokine (C-C Motif) Receptor 4 (CCR4))

Autre désignation: CD194 / CCR4 (CCR4 Produits)

Synonymes: anticorps CC-CKR-4, anticorps CD194, anticorps CKR4, anticorps CMKBR4, anticorps ChemR13, anticorps HGCN:14099, anticorps K5-5, anticorps Ccr4, anticorps C-C CKR-4, anticorps CHEMR1, anticorps Cmkbr4, anticorps LESTR, anticorps Sdf1r, anticorps C-C motif chemokine receptor 4, anticorps chemokine (C-C motif) receptor 4, anticorps CCR4, anticorps Ccr4

Sujet: Receptors for the C - C chemokine family include CCR1, CCR2A, CCR3, CCR4, CCR5 and the Duffy blood group antigen. The C - C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR4 is preferentially expressed on type 2 helper T (Th2-type) cells. In contrast to other chemokine receptors, the expression of CCR4 and CCR8 on Th2 cells is transiently increased following TCR and CD28 engagement. Moreover, activated Th1 cells up regulate CCR4 expression and functional responsiveness to thymus- and activation-regulated chemokine. CCR4 mediates inflammatory responses and HIV-1 infections. It binds beta-family chemokines (CC motif) such as TARC (thymus and activation-regulated chemokine) and MDC (macrophage-derived chemokine).Synonyms: C-C CKR-4, C-C chemokine receptor type 4, CC-CKR-4, CCR-4, CMKBR4, K5-5

ID gène: 4887

NCBI Accession: NP_000901

UniProt: P51679