CRYbA4 anticorps (N-Term)
Aperçu rapide pour CRYbA4 anticorps (N-Term) (ABIN488078)
Antigène
Voir toutes CRYbA4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 1-185, N-Term
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Specificité
- Recognizes Beta-crystallin A4 (1-150).
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse (91 %), Rat (91 %), Bovine (94 %), Dog (94 %), Monkey (96 %).
Species reactivity (tested):Human, Mouse. -
Purification
- Antigen-Affinity Chromatography.
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Immunogène
- Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 185 of Beta-Crystallin A4 Genename: CRYBA4
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Indications d'application
- This antibody is suitable for use in Immunofluorescence/Immunocytochemistry andWestern blotting. Recommended Dilutions: Western blotting: 1/500-1/3000. Immunofluorescence: 1/100-1/200.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1.0 mg/mL
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Buffer
- 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol and 0.01 % Thimerosal as preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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Stockage commentaire
- Store the antibody undiluted (in aliquots) at -20 °C.
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- CRYbA4 (Crystallin, beta A4 (CRYbA4))
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Autre désignation
- beta-Crystallin A4
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Sujet
- Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families, beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, is part of a gene cluster with beta-B1, beta-B2, and beta-B3.Synonyms: Beta-A4 crystallin, CRYBA4
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Poids moléculaire
- 22 kDa
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ID gène
- 1413, 9606
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UniProt
- P53673
Antigène
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