BAIAP2L1 anticorps (AA 1-226)

N° du produit ABIN488102

L’anticorps anti-BAIAP2L1 Polyclonal Lapin est utilisé pour la détection de BAIAP2L1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IF et IHC (fro).

Aperçu rapide pour BAIAP2L1 anticorps (AA 1-226) (ABIN488102)

Antigène: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BAIAP2L1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-BAIAP2L1 anticorps

Épitope: AA 1-226

Specificité: Recognizes BAIAP2L1.

Réactivité croisée (Details): Species reactivity (expected):Mouse (94 %) and Rat (94 %).
Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography

Immunogène: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 226 of BAIAP2L1 Genename: BAIAP2L1

Information d'application

Indications d'application: Western blot: 1/500-1/3000. Positive Controls: 293T, A431, HeLa, HepG2. Immunofluorescence: 1/100-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.55 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7), 0.01 % Thimerosal

Agent conservateur: Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody undiluted (in aliquots) at -20 °C.

Détails sur BAIAP2L1

Antigène: BAIAP2L1 (BAI1-Associated Protein 2-Like-1 (BAIAP2L1))

Autre désignation: BAIAP2L1

Sujet: This gene encodes a member of the IMD (IRSp53/MIM homology domain) family. Members of this family can be subdivided in two groups, the IRSp53-like and MIM-like, based on the presence or absence of the SH3 (Src homology 3) domain. The protein encoded by this gene contains a conserved IMD, also known as F-actin bundling domain, at the N-terminus, and a canonical SH3 domain near the C-terminus, so it belongs to the IRSp53-like group. This protein is the substrate for insulin receptor tyrosine kinase and binds to the small GTPase Rac. It is involved in signal transduction pathways that link deformation of the plasma membrane and remodeling of the actin cytoskeleton. It also promotes actin assembly and membrane protrusions when overexpressed in mammalian cells, and is essential to the formation of a potent actin assembly complex during EHEC (Enterohemorrhagic Escherichia coli) pedestal formation. [provided by RefSeq].Synonyms: BAI1-associated protein 2-like 1, Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1, IRTKS, Insulin receptor tyrosine kinase substrate

ID gène: 55971, 9606

UniProt: Q9UHR4

Pathways: Regulation of Actin Filament Polymerization