ABAT anticorps (AA 388-500)

N° du produit ABIN4886408

Détail du produit anti-ABAT anticorps

Antigène: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Épitope: AA 388-500

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ABAT est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for 4-aminobutyrate aminotransferase, mitochondrial(ABAT) detection. Tested with WB in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for 4-aminobutyrate aminotransferase, mitochondrial(ABAT) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: 4-aminobutyrate aminotransferase
Protein Name: 4-aminobutyrate aminotransferase, mitochondrial

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human ABAT recombinant protein (Position: K388-K500). Human ABAT shares 93.9% and 94.5% amino acid (aa) sequence identity with mouse and rat ABAT, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur ABAT

Antigène: ABAT (4-Aminobutyrate Aminotransferase (ABAT))

Autre désignation: ABAT (ABAT Produits)

Synonymes: anticorps cb880, anticorps fj82a01, anticorps wu:fj82a01, anticorps BA0325, anticorps PSPTO0259, anticorps PSPTO0301, anticorps PSPTO1890, anticorps GABA-AT, anticorps GABAT, anticorps NPD009, anticorps GABA-T, anticorps L-AIBAT, anticorps 9630038C02Rik, anticorps AI255750, anticorps ENSMUSG00000051226, anticorps Gabaat, anticorps Gabat, anticorps Gm9851, anticorps I54, anticorps Laibat, anticorps X61497, anticorps beta-AlaAT, anticorps 4-aminobutyrate aminotransferase, anticorps 4-aminobutyrate--2-oxoglutarate transaminase, anticorps GABA aminotransferase PLP-dependent PuuE, anticorps 4-aminobutyrate aminotransferase, mitochondrial, anticorps aspartate aminotransferase family protein, anticorps 4-aminobutyrate aminotransferase S homeolog, anticorps ABAT, anticorps abat, anticorps gabT, anticorps puuE, anticorps gabT-1, anticorps gabT-2, anticorps gabT-3, anticorps CNE01830, anticorps Mmwyl1_0047, anticorps CpipJ_CPIJ008729, anticorps KCR_RS04555, anticorps Bcenmc03_4909, anticorps Hden_0972, anticorps Dbac_2000, anticorps Mesil_2400, anticorps Trad_0121, anticorps abat.S, anticorps Abat

Sujet: 4-Aminobutyrate aminotransferase is a protein that in humans is encoded by the ABAT gene. ABAT is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5- phosphate. The protein sequence is over 95 % similar to the pig protein. GABA is estimated to be present in nearly one-third of humans ynapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractoryseizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Synonyms: ABAT | GABA aminotransferase | GABA AT | GABA T | GABA transaminase | GABA transferase | GABA-AT | GABA-T | GABAT | L AIBAT | L-AIBAT | LAIBAT | NPD009 | P80404

ID gène: 18

UniProt: P80404

Pathways: Monocarboxylic Acid Catabolic Process