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ACTN3 anticorps (C-Term)

ACTN3 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN4886420
  • Antigène Voir toutes ACTN3 Anticorps
    ACTN3 (Actinin, alpha 3 (ACTN3))
    Épitope
    • 7
    • 7
    • 7
    • 7
    • 6
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 574-617, C-Term
    Reactivité
    • 46
    • 22
    • 22
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Souris, Rat
    Hôte
    • 47
    • 2
    Lapin
    Clonalité
    • 45
    • 4
    Polyclonal
    Conjugué
    • 28
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ACTN3 est non-conjugé
    Application
    • 36
    • 22
    • 20
    • 9
    • 8
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Alpha-actinin-3(ACTN3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Séquence
    EADRERGAIM GIQGEIQKIC QTYGLRPCST NPYITLSPQD INT
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Alpha-actinin-3(ACTN3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: actinin alpha 3 (gene/pseudogene)
    Protein Name: Alpha-actinin-3
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of human ACTN3 (574-617aa EADRERGAIMGIQGEIQKICQTYGLRPCSTNPYITLSPQDINT K), different from the related mouse sequence by five amino acids.
    Isotype
    IgG
    Top Product
    Discover our top product ACTN3 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    ACTN3 (Actinin, alpha 3 (ACTN3))
    Autre désignation
    ACTN3 (ACTN3 Produits)
    Synonymes
    anticorps CG8953, anticorps Dmel\\CG8953, anticorps ORF1, anticorps acta-3, anticorps dabp, anticorps ACTN2, anticorps actn3, anticorps actnl, anticorps zgc:63559, anticorps fb95c03, anticorps wu:fb95c03, anticorps wu:fc11d03, anticorps zgc:77243, anticorps actinin alpha 3 (gene/pseudogene), anticorps actinin alpha 3, anticorps alpha actinin 3, anticorps actinin alpha 3a, anticorps actinin alpha 3 (gene/pseudogene) L homeolog, anticorps alpha-actinin-3, anticorps actinin alpha 3b, anticorps ACTN3, anticorps Actn3, anticorps actn3a, anticorps actn3.L, anticorps actn3, anticorps LOC100439754, anticorps actn3b
    Sujet
    Alpha-actinin-3, also known as alpha-actinin skeletal muscle isoform 3 or F-actin cross-linking protein, is a protein that in humans is encoded by the ACTN3 gene. This gene encodes a member of the alpha-actin binding protein gene family. The encoded protein is primarily expressed in skeletal muscle and functions as a structural component of sarcomeric Z line. This protein is involved in crosslinking actin containing thin filaments. An allelic polymorphism in this gene results in both coding and non-coding variants, the reference genome represents the coding allele. The non-functional allele of this gene is associated with elite athlete status.

    Synonyms: Actinin alpha 3 | Alpha-Actinin 3 | Alpha-actinin-3 | ACTN 3 | ACTN3 | Q08043
    ID gène
    89
    UniProt
    Q08043
    Pathways
    Cell-Cell Junction Organization
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