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AQP11 anticorps (N-Term)

Cet anticorps anti-AQP11 est un anticorps Lapin Polyclonal détectant AQP11 dans WB. Adapté pour Humain, Souris et Rat.
N° du produit ABIN4886472

Aperçu rapide pour AQP11 anticorps (N-Term) (ABIN4886472)

Antigène

Voir toutes AQP11 Anticorps
AQP11 (Aquaporin 11 (AQP11))

Reactivité

Humain, Souris, Rat

Hôte

  • 26
Lapin

Clonalité

  • 26
Polyclonal

Conjugué

  • 13
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp AQP11 est non-conjugé

Application

  • 18
  • 16
  • 13
  • 10
  • 4
  • 4
  • 3
  • 3
Western Blotting (WB)
  • Épitope

    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 35-70, N-Term

    Fonction

    Anti-AQP11 Antibody Picoband®

    Séquence

    ARQQLHRPVA HAFVLEFLAT FQLCCCTHEL QLLSEQ

    Réactivité croisée (Details)

    No cross-reactivity with other proteins.

    Attributs du produit

    Anti-AQP11 Antibody Picoband® (ABIN4886472). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the N-terminus of human AQP11, different from the related mouse sequence by two amino acids, and from the related rat sequence by three amino acids.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. Morishita, Y., Matsuzaki, T., Hara-chikuma, M., Andoo, A., Shimono, M., Matsuki, A., Kobayashi, K., Ikeda, M., Yamamoto, T., Verkman, A., Kusano, E., Ookawara, S., Takata, K., Sasaki, S., Ishibashi, K.Disruption of aquaporin-11 produces polycystic kidneys following vacuolization of the proximal tubule. Molec. Cell. Biol. 25: 7770-7779, 2005.

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    AQP11 (Aquaporin 11 (AQP11))

    Autre désignation

    AQP11

    Sujet

    Synonyms: Aquaporin-11,AQP-11,AQP11,AQPX1,PSEC0027,

    Tissue Specificity: Liver. .

    Background: AQP11 has a unique asparagine-proline-alanine (NPA) box distinct from those of other AQPs, suggesting a different pore structure and function. Using Northern blot analysis, they detected highest expression of mouse Aqp11 in testis, followed by liver and kidney. Expression was much weaker in heart, brain, and muscle. Western blot analysis of mouse kidney membrane fractions detected Aqp11 at an apparent molecular mass of 26 kD, lower than the calculated molecular mass of 30 kD. Immunohistochemical analysis localized Aqp11 to mouse renal proximal tubule cells, where it showed a perinuclear distribution. Fluorescence-tagged Aqp11 localized with an endoplasmic reticulum marker.

    Poids moléculaire

    30 kDa

    ID gène

    282679
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