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Osteocalcin anticorps (AA 50-99)

BGLAP Reactivité: Rat IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN4886487
  • Antigène Voir toutes Osteocalcin (BGLAP) Anticorps
    Osteocalcin (BGLAP)
    Épitope
    • 15
    • 10
    • 9
    • 8
    • 8
    • 8
    • 7
    • 7
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 50-99
    Reactivité
    • 101
    • 42
    • 21
    • 20
    • 19
    • 15
    • 15
    • 10
    • 8
    • 7
    • 4
    • 1
    • 1
    • 1
    Rat
    Hôte
    • 91
    • 32
    • 2
    • 2
    • 1
    Lapin
    Clonalité
    • 95
    • 33
    Polyclonal
    Conjugué
    • 74
    • 13
    • 11
    • 8
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp Osteocalcin est non-conjugé
    Application
    • 97
    • 71
    • 50
    • 15
    • 15
    • 14
    • 14
    • 9
    • 9
    • 8
    • 8
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Osteocalcin(BGLAP) detection. Tested with IHC-P in Rat.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Osteocalcin(BGLAP) detection. Tested with IHC-P in Rat.
    Gene Name: bone gamma-carboxyglutamate (gla) protein
    Protein Name: Osteocalcin
    Purification
    Immunogen affinity purified.
    Immunogène
    E. coli-derived rat Osteocalcin recombinant protein (Position: Y50-V99). Rat Osteocalcin shares 80.9% and 68.9% amino acid (aa) sequence identity with human and mouse Osteocalcin, respectively.
    Isotype
    IgG
    Top Product
    Discover our top product BGLAP Anticorps primaire
  • Indications d'application
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Song, Wang, Zeng, Wang: "Synergistic effects of fibroblast growth factor-2 and bone morphogenetic protein-2 on bone induction." dans: Molecular medicine reports, Vol. 16, Issue 4, pp. 4483-4492, (2018) (PubMed).

    Liu, Ma, Wang, Zhu, Yang, Mei: "Demineralized bone matrix used for direct pulp capping in rats." dans: PLoS ONE, Vol. 12, Issue 3, pp. e0172693, (2017) (PubMed).

    Yang, Baban, Isales, Shi: "Role of glucocorticoid-induced leucine zipper (GILZ) in inflammatory bone loss." dans: PLoS ONE, Vol. 12, Issue 8, pp. e0181133, (2017) (PubMed).

    Che, Guo, Li, Wang, Wei: "Intramuscular injection of bone marrow mononuclear cells contributes to bone repair following midpalatal expansion in rats." dans: Molecular medicine reports, Vol. 13, Issue 1, pp. 681-8, (2016) (PubMed).

    Yin, Cheng, Qin, Yu, Yu, Zhong, Sun, Zhang: "Effects of Naringin on Proliferation and Osteogenic Differentiation of Human Periodontal Ligament Stem Cells In Vitro and In Vivo." dans: Stem cells international, Vol. 2015, pp. 758706, (2015) (PubMed).

    Cheng, Wang, Zhang, Shi: "The osteogenic potential of mesoporous bioglasses/silk and non-mesoporous bioglasses/silk scaffolds in ovariectomized rats: in vitro and in vivo evaluation." dans: PLoS ONE, Vol. 8, Issue 11, pp. e81014, (2014) (PubMed).

    Chen, Bai, Liao, Peng, Wu, Wang, Zeng, Xie: "Electrospun poly(L-lactide)/poly(?-caprolactone) blend nanofibrous scaffold: characterization and biocompatibility with human adipose-derived stem cells." dans: PLoS ONE, Vol. 8, Issue 8, pp. e71265, (2013) (PubMed).

  • Antigène
    Osteocalcin (BGLAP)
    Autre désignation
    BGLAP (BGLAP Produits)
    Synonymes
    anticorps BGP, anticorps OC, anticorps OCN, anticorps Bglap1, anticorps Bglap2, anticorps OG1, anticorps mOC-A, anticorps Bgp, anticorps Bgpr, anticorps Bgpra, anticorps bgp, anticorps LOC792433, anticorps ocn, anticorps GLA, anticorps BGLAP, anticorps PMF1, anticorps bone gamma-carboxyglutamate protein, anticorps bone gamma carboxyglutamate protein, anticorps bone gamma-carboxyglutamate protein S homeolog, anticorps bone gamma-carboxyglutamate (gla) protein, anticorps osteocalcin, anticorps polyamine-modulated factor 1, anticorps BGLAP, anticorps Bglap, anticorps bglap.S, anticorps bglap, anticorps ocn, anticorps LOC100529177, anticorps LOC100146589
    Sujet
    Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time directing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.

    Synonyms: BGLAP | Bone Gla protein | ocn | OSTCN HUMAN | Osteocalcin | P04640
    ID gène
    25295
    UniProt
    P04640
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