CD58 anticorps (AA 29-215)
Aperçu rapide pour CD58 anticorps (AA 29-215) (ABIN4886530)
Antigène
Voir toutes CD58 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 29-215
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Fonction
- Anti-LFA3/CD58 Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Attributs du produit
- Anti-LFA3/CD58 Antibody (ABIN4886530). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived human LFA3 recombinant protein (Position: F29-R215).
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL
Flow Cytometry, 1-3 μg/1x106cells
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CD58
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Autre désignation
- CD58
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Sujet
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Synonyms: Lymphocyte function-associated antigen 3,Ag3,Surface glycoprotein LFA-3,CD58,CD58,LFA3,
Tissue Specificity: Widely expressed.
Background: CD58, or lymphocyte function-associated antigen 3 (LFA-3), is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. It binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. This adhesion occurs as part of the transitory initial encounters between T cells and Antigen Presenting Cells before T cell activation, when T cells are roaming the lymph nodes looking at the surface of APCs for peptide:MHC complexes the T-cell receptors are reactive to. The LFA3 gene is mapped to chromosome 1p13, which is the same location as CD2.
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Poids moléculaire
- 26 kDa
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ID gène
- 965
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UniProt
- P19256
Antigène
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