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CPB2 anticorps (AA 165-387)

CPB2 Reactivité: Souris WB Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN4886546
  • Antigène Voir toutes CPB2 Anticorps
    CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
    Épitope
    • 15
    • 6
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 165-387
    Reactivité
    • 53
    • 22
    • 11
    • 2
    • 1
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 57
    • 6
    • 4
    Lapin
    Clonalité
    • 62
    • 5
    Polyclonal
    Conjugué
    • 31
    • 8
    • 7
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp CPB2 est non-conjugé
    Application
    • 36
    • 20
    • 13
    • 13
    • 13
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Fonction
    Rabbit IgG polyclonal antibody for Carboxypeptidase B2(CPB2) detection. Tested with WB in Mouse.
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Carboxypeptidase B2(CPB2) detection. Tested with WB in Mouse.
    Gene Name: carboxypeptidase B2
    Protein Name: Carboxypeptidase B2
    Purification
    Immunogen affinity purified.
    Immunogène
    E. coli-derived mouse CPB2 recombinant protein (Position: K165-D387). Mouse CPB2 shares 86.1% and 96.9% amino acid (aa) sequence identity with human and rat CPB2, respectively.
    Isotype
    IgG
    Top Product
    Discover our top product CPB2 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Qin, Zeng, Tian, Deng, Ren, Zheng, Li, Li, Liao, Chen: "Involvement of prolylcarboxypeptidase in the effect of rutaecarpine on the regression of mesenteric artery hypertrophy in renovascular hypertensive rats." dans: Clinical and experimental pharmacology & physiology, Vol. 36, Issue 3, pp. 319-24, (2009) (PubMed).

  • Antigène
    CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
    Autre désignation
    CPB2 (CPB2 Produits)
    Synonymes
    anticorps CPU, anticorps PCPB, anticorps TAFI, anticorps 1110032P04Rik, anticorps 4930405E17Rik, anticorps AI255929, anticorps CPR, anticorps Cpu, anticorps pCPB, anticorps zgc:112493, anticorps carboxypeptidase B2, anticorps carboxypeptidase B2 (plasma), anticorps CPB2, anticorps Cpb2, anticorps cpb2
    Sujet
    Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

    Synonyms: Carboxypeptidase U | CarboxypeptidaseU | CarboxypeptidaseB2 | Carboxypeptidase B2 | CP B2 | CPB2 | CPB 2 | CPU | PCPB | Procarboxypeptidase B | Procarboxypeptidase R | Procarboxypeptidase U | TAFI | Q96IY4
    ID gène
    56373
    Pathways
    Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
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