Diazepam Binding Inhibitor anticorps (AA 2-87)

N° du produit ABIN4886558

Détail du produit anti-Diazepam Binding Inhibitor anticorps

Antigène: Diazepam Binding Inhibitor (DBI)

Épitope: AA 2-87

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Diazepam Binding Inhibitor est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Acyl-CoA-binding protein(DBI) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Acyl-CoA-binding protein(DBI) detection. Tested with WB, IHC-P in Human.
Gene Name: diazepam binding inhibitor, acyl-CoA binding protein
Protein Name: Acyl-CoA-binding protein

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human DBI recombinant protein (Position: S2-I87). Human DBI shares 77.9% amino acid (aa) sequence identity with both mouse and rat DBI.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur Diazepam Binding Inhibitor

Antigène: Diazepam Binding Inhibitor (DBI)

Autre désignation: DBI (DBI Produits)

Synonymes: anticorps ACBD1, anticorps ACBP, anticorps CCK-RP, anticorps EP, anticorps dbib, anticorps DBI, anticorps wu:fb63e10, anticorps zgc:56108, anticorps zgc:77734, anticorps Acbp, anticorps endozepine, anticorps Acoabp3, anticorps Ep, anticorps Odn, anticorps RNACOABP3, anticorps Ttn, anticorps acbd1, anticorps acbp, anticorps cck-rp, anticorps dbi, anticorps dbi-a, anticorps dbi-b, anticorps dbia, anticorps diazepam binding inhibitor, acyl-CoA binding protein, anticorps diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) S homeolog, anticorps diazepam-binding inhibitor, anticorps diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein), anticorps acyl-CoA-binding protein, anticorps diazepam binding inhibitor, anticorps diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein) L homeolog, anticorps DBI, anticorps dbi.S, anticorps dbi, anticorps LOC706367, anticorps Dbi, anticorps dbi.L

Sujet: Acyl-CoA-binding protein is a protein that in humans is encoded by the DBI gene. This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene.

Synonyms: ACBD 1 | ACBD1 | ACBP | CCK RP | CCKRP | DBI | Endozepine | EP | P07108

ID gène: 1622

UniProt: P07108