FSHR anticorps (AA 18-187)

N° du produit ABIN4886595

Cet anticorps anti-FSHR est un anticorps Lapin Polyclonal détectant FSHR dans WB. Adapté pour Humain, Souris et Rat. Ce Primary Antibody a été cité dans 1 publication.

Aperçu rapide pour FSHR anticorps (AA 18-187) (ABIN4886595)

Antigène: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FSHR est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-FSHR anticorps

Épitope: AA 18-187

Fonction: Anti-FSH Receptor/FSHR Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-FSH Receptor/FSHR Antibody Picoband® (ABIN4886595). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human FSH Receptor recombinant protein (Position: C18-N187). Human FSH Receptor shares 91.2% and 90% amino acid (aa) sequence identity with mouse and rat FSH Receptor, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Gromoll, J., Ried, T., Holtgreve-Grez, H., Nieschlag, E., Gudermann, T. Localization of the human FSH receptor to chromosome 2p21 using a genomic probe comprising exon 10. J. Molec. Endocr. 12: 265-271, 1994.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Références pour anticorps anti-FSHR (ABIN4886595)

Wu, Shi, Gong, Yu, Chen, Wang, Sun: "Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome." dans: PLoS ONE, Vol. 10, Issue 5, pp. e0127595, (2016) (PubMed).

Détails sur FSHR

Antigène: FSHR (Follicle Stimulating Hormone Receptor (FSHR))

Autre désignation: FSHR

Sujet:

Synonyms: Follicle-stimulating hormone receptor,FSH-R,Follitropin receptor,FSHR,LGR1,

Tissue Specificity: Sertoli cells and ovarian granulosa cells.

Background: The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that interacts with the follicle-stimulating hormone (FSH) and represents a G protein-coupled receptor (GPCR). This FSHR gene is mapped to chromosome 2p21 by fluorescence in situ hybridization. The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants.

Poids moléculaire: 78 kDa

ID gène: 2492

UniProt: P23945

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Hormone Metabolic Process, Platelet-derived growth Factor Receptor Signaling