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HMGB2 anticorps (N-Term)

HMGB2 Reactivité: Humain, Souris, Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN4886620
  • Antigène Voir toutes HMGB2 Anticorps
    HMGB2 (High Mobility Group Box 2 (HMGB2))
    Épitope
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-97, N-Term
    Reactivité
    • 57
    • 29
    • 21
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    Humain, Souris, Rat
    Hôte
    • 45
    • 12
    Lapin
    Clonalité
    • 43
    • 14
    Polyclonal
    Conjugué
    • 39
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp HMGB2 est non-conjugé
    Application
    • 38
    • 21
    • 16
    • 15
    • 10
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for High mobility group protein B2(HMGB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Séquence
    KSDKARYDRE MKNYVPPKGD KKGKKKDPNA PKR
    Réactivité croisée (Details)
    No cross reactivity with other proteins.
    Attributs du produit
    Rabbit IgG polyclonal antibody for High mobility group protein B2(HMGB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: high mobility group box 2
    Protein Name: High mobility group protein B2
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the N-terminus of human HMGB2 (65-97aa KSDKARYDREMKNYVPPKGDKKGKKKDPNAPKR), identical to the related mouse and rat sequences.
    Isotype
    IgG
    Top Product
    Discover our top product HMGB2 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Antigène
    HMGB2 (High Mobility Group Box 2 (HMGB2))
    Autre désignation
    HMGB2 (HMGB2 Produits)
    Synonymes
    anticorps HMG2, anticorps C80539, anticorps HMG-2, anticorps Hmg2, anticorps HIGH MOBILITY GROUP BETA 1, anticorps HMG BETA 1, anticorps NFD02, anticorps NFD2, anticorps NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 02, anticorps NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP D 2, anticorps high mobility group B2, anticorps hmgb2, anticorps hmgb2l, anticorps im:6909096, anticorps wu:fa20b02, anticorps zgc:101854, anticorps wu:fb22b10, anticorps wu:fc95d12, anticorps zgc:123215, anticorps high mobility group box 2, anticorps high mobility group box 2 S homeolog, anticorps high mobility group B2, anticorps high mobility group box 2b, anticorps high mobility group box 2a, anticorps HMGB2, anticorps Hmgb2, anticorps hmgb2.S, anticorps hmgb2b, anticorps hmgb2a
    Sujet
    High-mobility group protein B2, also known as high-mobility group protein 2 (HMG-2), is a protein that in humans is encoded by the HMGB2 gene. This gene encodes a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

    Synonyms: C80539 | HMG2 | HMG-2 | HMG 2 | HMG B2 | HMGB2 | P26583
    ID gène
    3148
    UniProt
    P26583
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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