ZBTB16 anticorps (AA 1-165)

N° du produit ABIN4886774

L’anticorps Lapin Polyclonal anti-ZBTB16 a été validé pour WB. Il convient pour détecter ZBTB16 dans des échantillons de Humain et Rat.

Aperçu rapide pour ZBTB16 anticorps (AA 1-165) (ABIN4886774)

Antigène: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZBTB16 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-ZBTB16 anticorps

Épitope: AA 1-165

Fonction: Anti-Plzf/ZBTB16 Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Plzf/ZBTB16 Antibody Picoband® (ABIN4886774). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Plzf recombinant protein (Position: M1-E165).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Kovalovsky D, Uche OU, Eladad S, Hobbs RM, Yi W, Alonzo E, Chua K, Eidson M, et al. (2008). "The BTB-zinc finger transcriptional regulator, PLZF, controls the development of iNKT cell effector functions". Nature Immunology 9 (9): 1055-64. 2. Savage AK, Constantinides MG, Han J, Picard D, Martin E, Li B, Lantz O, Bendelac A (2008). "The transcription factor PLZF (Zbtb16) s the effector program of the NKT cell lineage".Immunity 29 (3): 391-403. 3. Zhang T, Xiong H, Kan LX, Zhang CK, Jiao XF, Fu G, Zhang QH, Lu L, et al. (1999). "Genomic sequence, structural organization, molecular evolution, and aberrant rearrangement of promyelocytic leukemia zinc finger gene".Proceedings of the National Academy of Sciences of the United States of America 96 (20): 11422-7.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur ZBTB16

Antigène: ZBTB16 (Zinc Finger and BTB Domain Containing 16 (ZBTB16))

Autre désignation: ZBTB16

Sujet:

Synonyms: Zinc finger and BTB domain-containing protein 16,Promyelocytic leukemia zinc finger protein,Zinc finger protein 145,Zinc finger protein PLZF,ZBTB16,PLZF, ZNF145,

Tissue Specificity: Within the hematopoietic system, PLZF is expressed in bone marrow, early myeloid cell lines and peripheral blood mononuclear cells. Also expressed in the ovary, and at lower levels, in the kidney and lung.

Background: Zinc finger and BTB domain-containing protein 16 is a protein that in humans is encoded by the ZBTB16 gene. This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized.

Poids moléculaire: 74 kDa

ID gène: 7704

UniProt: Q05516

Pathways: Positive Regulation of fat Cell Differentiation