8-OHDG anticorps

N° du produit ABIN488679

Cité dans 3 publications. Cet anticorps anti-8-OHDG Monoclonal Souris (Clone 15A3) (ABIN488679) détecte spécifiquement 8-OHDG dans ELISA, AC et IHC (fp).

Aperçu rapide pour 8-OHDG anticorps (ABIN488679)

Antigène: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp 8-OHDG est non-conjugé

Application: ELISA, Affinity Chromatography (AC), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))

Clone: 15A3

Détail du produit anti-8-OHDG anticorps

Fonction: Anti-8-Hydroxyguanosine | DNA/RNA oxidative damage (clone 15A3)

Specificité: Recognizes markers of oxidative damage to DNA (8-hydroxy-2?-deoxyguanosine,8-hydroxyguanine and 8-hydroxyguanosine).

Réactivité croisée (Details): Recognizes markers of oxidative damage to DNA (8-hydroxy-2'-deoxyguanosine, 8-hydroxyguanine and 8-hydroxyguanosine)
Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Purification: Protein G purified

Immunogène: 8-hydroxy-guanosine-BSA and - casein conjugates

Isotype: IgG2a

Information d'application

Indications d'application: The optimal working dilution should be determined by the investigator

Commentaires:

protocol for immunostaining using this antibody can be found here

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Total IgG fraction. Protein G purified.

Conseil sur la manipulation: Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube

Stock: -20 °C

Stockage commentaire: Store lyophilized/reconstituted at -20°C, once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.

Références pour anticorps anti-8-OHDG (ABIN488679)

Haigh, Drew: "Cavitation during the protein misfolding cyclic amplification (PMCA) method--The trigger for de novo prion generation?" dans: Biochemical and biophysical research communications, Vol. 461, Issue 3, pp. 494-500, (2015) (PubMed).

Bobal, Otevrel, Poborilova, Vaverkova, Csollei, Babula: "Application of BY-2 cell model in evaluating an effect of newly prepared potential calcium channel blockers." dans: Pakistan journal of pharmaceutical sciences, Vol. 28, Issue 4, pp. 1281-93, (2015) (PubMed).

Pilger, Rüdiger: "8-Hydroxy-2'-deoxyguanosine as a marker of oxidative DNA damage related to occupational and environmental exposures." dans: International archives of occupational and environmental health, Vol. 80, Issue 1, pp. 1-15, (2006) (PubMed).

Détails sur 8-OHDG

Antigène: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Autre désignation: 8-Hydroxyguanosine

Classe de substances: Chemical

Sujet:

Background: Oxidative derivate of guanosine is called 8-Hydroxyguanosine (8OHdG) and is used as a popular biomarker of oxidative stress.

Additional information: Protein G purified IgG2B in PBS, pH 7,4 with 0,09 % sodium azide and 50 % glycerol at concentration 0,65 mg/mL