CD81 anticorps

N° du produit ABIN4888503

Cet anticorps Souris Monoclonal détecte spécifiquement CD81 dans FACS, WB, IP, Func, IHC (p) et ICC. Il présente une réactivité envers Humain, Lapin et Cat.

Aperçu rapide pour CD81 anticorps (ABIN4888503)

Antigène: CD81

Reactivité: Humain, Lapin, Cat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD81 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Clone: M38

Détail du produit anti-CD81 anticorps

Fonction: Anti-Hu CD81 Purified Low Endotoxin

Specificité: The antibody M38 reacts with an extracellular epitope of CD81, a 25 kDa member of the tetraspanin family, expressed on majority of cells.

Réactivité croisée (Details): Human, Feline (Cat), Rabbit

Purification: Purified by protein-A affinity chromatography.

Pureté: > 95 % (by SDS-PAGE)

niveau d'endotoxine: Endotoxin level is less than 0.01 EU/µg of the protein, as determined by the LAL test.

Immunogène: MOLT-4 (human T-ALL cell line)

Isotype: IgG1

Information d'application

Indications d'application: Functional application: In human MOLT-4 T-cell line the antibody M38 inhibits syncytium formation induced by coculture with human T-cell leukemia virus type 1 (HTLV-1)-positive human T-cell lines.
Flow cytometry: recommended dilution: 1 μg/mL.
Western blotting: recommended dilution: 1-2 μg/mL, positive control: Jurkat cells, non-reducing conditions.

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.4

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur CD81

Antigène: CD81

Autre désignation: CD81

Sujet: CD81 Molecule,CD81 (TAPA-1), a member of the tetraspanin family, is expressed on virtually all nucleated cells, but above all on germinal center B cells. CD81 forms complexes with other tetraspanin proteins, integrins, coreceptors, MHC class I and II molecules, and influences adhesion, morphology, activation, proliferation and differentiation of B, T and other cells, e.g. in muscles CD81 promotes cell fusion and myotube maintenance. CD81 has been also identified as a receptor for the hepatitis C virus.,S5.7, CVID6, TAPA1, TSPAN28

ID gène: 975

UniProt: P60033

Pathways: Inositol Metabolic Process, Hepatitis C