EGLN3 anticorps (Internal Region)

N° du produit ABIN4889115

Cet anticorps anti-EGLN3 est un anticorps Lapin Polyclonal détectant EGLN3 dans WB, ELISA et IHC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour EGLN3 anticorps (Internal Region) (ABIN4889115)

Antigène: EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EGLN3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-EGLN3 anticorps

Épitope: Internal Region

Specificité: Reacts with EGLN3 from human, mouse and rat

Purification: Purified (protein A)

Immunogène: Synthetic peptide of derived from internal part of human EGLN3.

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only:
IHC1:100 - 1:1000 WB1:200 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur EGLN3

Antigène: EGLN3 (Egl-9 Family Hypoxia Inducible Factor 3 (EGLN3))

Autre désignation: EGLN3

Sujet: Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of the oxygen-dependent degradation (ODD) domains (N-terminal, NODD, and C-terminal, CODD) of HIF1A. Also hydroxylates HIF2A. Has a preference for the CODD site for both HIF1A and HIF2A. Hydroxylation on the NODD site by EGLN3 appears to require prior hydroxylation on the CODD site.

ID gène: 112399

UniProt: Q9H6Z9

Pathways: Positive Regulation of Endopeptidase Activity