KEAP1 anticorps (C-Term)
-
- Antigène Voir toutes KEAP1 Anticorps
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
-
Épitope
- C-Term
-
Reactivité
- Humain, Porc, Cobaye
-
Hôte
- Lapin
-
Clonalité
- Polyclonal
-
Conjugué
- Cet anticorp KEAP1 est non-conjugé
-
Application
- Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)
- Specificité
- Reacts with KEAP1 from human, pig, guinea pig, sheep and other species (due to 100 % sequence homology)
- Purification
- Purified (protein A)
- Immunogène
- Synthetic peptide of derived from C terminal part of human KEAP1.
- Top Product
- Discover our top product KEAP1 Anticorps primaire
-
-
- Indications d'application
-
Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB(1:500 - 1:200) ICC/ IF(1:200 - 1:1000) - Restrictions
- For Research Use only
-
- Format
- Lyophilized
- Reconstitution
- Must be reconstituted in distilled water.
- Concentration
- 1 mg/mL
- Buffer
- Tris 0,1M, glycine 0,1M
- Stock
- 4 °C/-20 °C
- Stockage commentaire
- Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
- Date de péremption
- 6 months
-
- Antigène
- KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
- Autre désignation
- KEAP1 (KEAP1 Produits)
- Synonymes
- anticorps INrf2, anticorps KLHL19, anticorps INRF2, anticorps mKIAA0132, anticorps Inrf2, anticorps fb36f11, anticorps keap1, anticorps wu:fb36f11, anticorps KEAP1, anticorps klhl19, anticorps zgc:171654, anticorps kelch like ECH associated protein 1, anticorps kelch-like ECH-associated protein 1, anticorps Kelch-like ECH-associated protein 1, anticorps kelch-like ECH-associated protein 1a, anticorps kelch like ECH associated protein 1 L homeolog, anticorps kelch-like ECH-associated protein 1b, anticorps KEAP1, anticorps Keap1, anticorps keap1a, anticorps keap1, anticorps keap1.L, anticorps keap1b
- Sujet
- Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.
- ID gène
- 9817
- UniProt
- Q14145
- Pathways
- Maintenance of Protein Location
-