MBD3 anticorps (C-Term)

N° du produit ABIN4889329

Cet anticorps Lapin Polyclonal détecte spécifiquement MBD3 dans WB, ELISA, IF et ICC. Il présente une réactivité envers Humain, Souris, Rat, Singe et Hamster.

Aperçu rapide pour MBD3 anticorps (C-Term) (ABIN4889329)

Antigène: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Reactivité: Humain, Souris, Rat, Singe, Hamster

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MBD3 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Détail du produit anti-MBD3 anticorps

Épitope: C-Term

Specificité: Reacts with MBD3 from human, mouse, rat, hamster, monkeys and other species (due to sequence homology)

Purification: Purified (protein A)

Immunogène: Synthetic peptide of derived from C terminal part of human MBD3.

Information d'application

Indications d'application:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M

Stock: 4 °C/-20 °C

Stockage commentaire: Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 6 months

Détails sur MBD3

Antigène: MBD3 (Methyl-CpG Binding Domain Protein 3 (MBD3))

Autre désignation: MBD3

Sujet: Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself. Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro). Binds to a lesser degree DNA containing unmethylated CpG dinucleotides. Recruits histone deacetylases and DNA methyltransferases.

ID gène: 53615

UniProt: O95983

Pathways: Chromatin Binding