PRNP anticorps (C-Term)

N° du produit ABIN4889437

Détail du produit anti-PRNP anticorps

Antigène: PRNP (Prion Protein (PRNP))

Épitope: C-Term

Reactivité: Humain, Rat, Boeuf (Vache), Mouton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp PRNP est non-conjugé

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Specificité: Reacts with full sequence PrP protein of brain tissue from different species (bovin, human, sheep, rat

Réactivité croisée: Mouton, Rat (Rattus)

Réactivité croisée (Details): .) Cross reacts with brain tissue from different species (bovin, human, sheep, rat ...)

Purification: Purified (protein A)

Immunogène: A 15 residue synthetic peptide derived from C-terminal domain of human PrP protein

Clone: 4H7

Isotype: IgG2a kappa

Information d'application

Indications d'application:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:200 - 1:1000) WB(1:200 - 1:1000)

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Stock: 4 °C/-20 °C

Stockage commentaire: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Date de péremption: 24 months

Détails sur PRNP

Antigène: PRNP (Prion Protein (PRNP))

Autre désignation: Prion Protein (PrP) (PRNP Produits)

Sujet: PrP is found in high quantity in the brain of humans and animals infected with neurodegenerative diseases known as transmissible spongiform encephalopathies or prion diseases, like: Creutzfeldt-Jakob disease (CJD), fatal familial insomnia (FFI), Gerstmann-Straussler disease (GSD), Huntington disease-like type 1 (HDL1) and kuru in humans, scrapie in sheep and goat, bovine spongiform encephalopathy (BSE) in cattle.

UniProt: P04156

Pathways: Transition Metal Ion Homeostasis, Activated T Cell Proliferation