CD17 anticorps
Reactivité: Humain
FACS
Hôte: Souris
Monoclonal
MEM-68
unconjugated
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- Antigène
- CD17
- Reactivité
- Humain
-
Hôte
- Souris
-
Clonalité
- Monoclonal
-
Conjugué
- Inconjugué
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Application
- Flow Cytometry (FACS)
- Specificité
- The mouse monoclonal antibody MEM-68 recognizes CD17, an extracellular membrane lipid moiety lactosylceramide expressed on granulocytes, monocytes and platelets.
- Réactivité croisée (Details)
- Human
- Purification
- Purified by sequential steps of physicochemical fractionation (differential precipitation and solid-phase chromatography methods).
- Pureté
- > 95 % (by SDS-PAGE)
- Immunogène
- Pre-B cell line NALM-6
- Clone
- MEM-68
- Isotype
- IgM
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-
- Indications d'application
- Flow cytometry: Recommended dilution: 2 μg/mL.
- Restrictions
- For Research Use only
-
- Concentration
- 1 mg/mL
- Buffer
- Tris buffered saline (TBS), pH 8.0, 15 mM sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Do not freeze.
- Stock
- 4 °C
- Stockage commentaire
- Store at 2-8°C. Do not freeze.
-
- Antigène
- CD17
- Sujet
- CD17, lactosylceramide, is an ubiquitous glycosphingolipid with uncharged disaccharide headgroup, highly enriched in lipid raft-derived structures. Besides playing a pivotal role in the biosynthesis of complex glycosphingilipids, lactosylceramide is involved in cell-cell and cell-matrix interactions and in signaling events linked to cell differentiation, development, apoptosis and oncogenesis. Lactosylceramide regulates integrin functions and production of nitric oxide. Its expression defines successive stages in the maturation of myeloid cells.,Lactosylceramide
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