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Collagen Type I anticorps

Cet anticorps anti-Collagen Type I est un anticorps Souris Monoclonal détectant Collagen Type I dans WB et ELISA. Adapté pour Humain, Rat et Souris.
N° du produit ABIN4901289

Aperçu rapide pour Collagen Type I anticorps (ABIN4901289)

Antigène

Voir toutes Collagen Type I (COL1) Anticorps
Collagen Type I (COL1) (Collagen, Type I (COL1))

Reactivité

  • 98
  • 60
  • 55
  • 18
  • 18
  • 17
  • 15
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Humain, Rat, Souris

Hôte

  • 68
  • 37
  • 13
Souris

Clonalité

  • 81
  • 37
Monoclonal

Conjugué

  • 59
  • 15
  • 6
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
Cet anticorp Collagen Type I est non-conjugé

Application

  • 77
  • 40
  • 38
  • 34
  • 31
  • 27
  • 27
  • 23
  • 18
  • 18
  • 17
  • 13
  • 11
  • 5
  • 4
  • 3
  • 1
Western Blotting (WB), ELISA
  • Fonction

    Collagen I is a protein encoded by the COL1A1 gene which is approximately 138,9 kDa. Collagen I is secreted into the extracellular space. It is involved in collagen chain trimerization, the integrin pathway, ERK signalling, focal adhesion and the phospholipase-C pathway. It is a pro-alpha-1 chain of type I collagen whose triple helix comprises two alpha-1 chains and one alpha-2 chain. Collagen I is expressed in the bone, skin, eye, lung and nervous system. Mutations in the COL1A1 gene may result in Caffey disease and Ehlers-Danlos syndrome. STJ98915 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous Collagen I protein.

    Specificité

    The antibody detects endogenous Collagen I protein.

    Attributs du produit

    Mouse Monoclonal to Collagen I.

    Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

    Immunogène

    synthetic peptide derived from Collagen I.
  • Indications d'application

    WB 1:500-2000
    ELISA 1:10000-20000

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1 mg/mL

    Buffer

    Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freeze/thaw cycles.

    Stock

    -20 °C

    Stockage commentaire

    Store at -20°C, and avoid repeat freeze-thaw cycles.
  • Antigène

    Collagen Type I (COL1) (Collagen, Type I (COL1))

    Autre désignation

    Collagen I

    Poids moléculaire

    139kDa

    ID gène

    1277

    UniProt

    P02452
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