CST3 anticorps
Aperçu rapide pour CST3 anticorps (ABIN4901344)
Antigène
Voir toutes CST3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Fonction
- Cystatin C is a protein encoded by the CST3 gene which is approximately 15,7 kDa. Cystatin C is secreted into the extracellular space. It is involved in the innate immune system, salivary secretion, neuroscience and plaque formation. This protein falls under the cystatin superfamily. It is the most abundant extracellular inhibitor of cysteine proteases and is thought to serve an important physiological role as a local regulator of this enzyme activity. Cystatin C is expressed in the nervous system, blood, kidney, saliva and muscle. Mutations in the CST3 gene may result in Creutzfeldt-Jakob disease. STJ97732 was developed from clone 7F11 and was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody detects endogenous levels of CST3.
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Specificité
- Cystatin C Mouse Monoclonal Antibody (7F11) detects endogenous levels of CST3
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Attributs du produit
- Mouse Monoclonal to Cystatin C.
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Purification
- The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
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Immunogène
- Recombinant peptide derived from Cystatin C
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Isotype
- IgG1
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Indications d'application
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WB 1:1000-2000
IHC 1:100-200 -
Commentaires
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Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C, and avoid repeat freeze-thaw cycles.
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- CST3 (Cystatin C (CST3))
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Autre désignation
- Cystatin C
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ID gène
- 1471
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UniProt
- P01034
Antigène
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