SIRT2 anticorps

N° du produit ABIN4902262

Cet anticorps Souris Monoclonal détecte spécifiquement SIRT2 dans WB et ELISA. Il présente une réactivité envers Humain, Rat et Souris.

Aperçu rapide pour SIRT2 anticorps (ABIN4902262)

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Reactivité: Humain, Rat, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp SIRT2 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 1D4-H11-H11

Détail du produit anti-SIRT2 anticorps

Fonction: Mouse monoclonal to SirT2.

Specificité: This antibody detects endogenous levels of SirT2 and does not cross-react with related proteins.

Attributs du produit: Mouse Monoclonal to SirT2.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogène: Purified recombinant human SirT2 protein expressed in E.coli.

Isotype: IgG2b

Information d'application

Indications d'application: WB 1:500-2000
ELISA 1:10000-20000

Commentaires:

Isoform 1 is expressed in heart, liver and skeletal muscle, weakly expressed in the cortex. Isoform 2 is strongly expressed in the cortex, weakly expressed in heart and liver. Weakly expressed in several malignancies including breast, liver, brain, kidney and prostate cancers compared to normal tissues. Weakly expressed in glioma cell lines compared to normal brain tissues (at protein level). Widely expressed. Highly expressed in heart, brain and skeletal muscle, while it is weakly expressed in placenta and lung. Down-regulated in many gliomas suggesting that it may act as a tumor suppressor gene in human gliomas possibly through the regulation of microtubule network.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C, and avoid repeat freeze-thaw cycles.

Détails sur SIRT2

Antigène: SIRT2 (Sirtuin 2 (SIRT2))

Autre désignation: SirT2

Poids moléculaire: 43kDa

ID gène: 22933

UniProt: Q8IXJ6