KLHL18 anticorps (AA 451-550) (Biotin)

N° du produit ABIN4911421

Cet anticorps Lapin Polyclonal détecte spécifiquement KLHL18 dans WB, ELISA, IHC (fro) et IHC (p). Il présente une réactivité envers Humain et Rat.

Aperçu rapide pour KLHL18 anticorps (AA 451-550) (Biotin) (ABIN4911421)

Antigène: KLHL18 (Kelch-Like 18 (KLHL18))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KLHL18 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-KLHL18 anticorps (Biotin)

Épitope: AA 451-550

Réactivité croisée: Humain, Rat

Homologie: Mouse,Horse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human KLHL18

Isotype: IgG

Information d'application

Indications d'application: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C for 12 months.

Date de péremption: 12 months

Détails sur KLHL18

Antigène: KLHL18 (Kelch-Like 18 (KLHL18))

Autre désignation: KLHL18

Sujet:

Synonyms: Kelch-like protein 18, KLHL18, KIAA0795, OK/SW-cl.74

Background: KLHL18 is a 574 amino acid protein that is related to the Drosophila kelch protein, which is required to maintain actin organization in ovarian ring canals. Mutations affecting Kelch function result in failure of Kelch to associate with the ring canals and subsequent female sterility. Human KLHL18 protein contains six kelch repeats, one BACK (BTB/Kelch associated) domain and one BTB (POZ) domain. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in transcriptional regulation via control of chromatin structure and function. There are two isoforms of KLHL18 that are produced as a result of alternative splicing events.

ID gène: 23276

UniProt: O94889