Lectin anticorps

N° du produit ABIN492365

L’anticorps Souris Monoclonal anti- a été validé pour EIA. Il convient pour détecter dans des échantillons de Mistletoe.

Aperçu rapide pour Lectin anticorps (ABIN492365)

Antigène: Lectin

Reactivité: Mistletoe

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Inconjugué

Application: Enzyme Immunoassay (EIA)

Clone: 2G8-F7

Détail du produit

Purification: Purified

Immunogène: Recombinant Mistletoe Lectin

Isotype: IgM

Information d'application

Indications d'application: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in aqua bidest to 1 mg/mL

Buffer: PBS, pH 7.4

Stock: 4 °C/-20 °C

Stockage commentaire: Store lyophilized at 2-8 °C and reconstituted at -20 °C. Avoid repeated freezing and thawing.
Shelf life: One year from despatch.

Date de péremption: 12 months

Détail du antigène

Antigène: Lectin

Sujet: Mistletoe lectin I (ML-I) is a type II ribosome-inactivating protein, which inhibits the protein biosynthesis at the ribosomal level. ML-I is composed of a catalytically active A-chain with rRNA N-glycosidase activity and a B-chain with carbohydrate binding specificities. Using comparative solid-phase binding assays along with electrospray ionization tandem mass spectrometry, ML-I was shown to preferentially bind to terminally α2-6-sialylated neolacto series gangliosides from human granulocytes.Researchers across Europe (centres include Moscow, Berlin and London) have been investigating what specific properties of Viscum album could affect cancer cells. They have confirmed that some chemicals in European mistletoe can have anticancer properties. These properties are linked to various cytotoxic and immuno-modulatory compounds found in mistletoe, mainly the chemicals known as Viscotoxins and Mistletoe Lectins.