LY9 anticorps
Aperçu rapide pour LY9 anticorps (ABIN492431)
Antigène
Voir toutes LY9 (CD229) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- The antibody recognizes CD229 / Ly9, a 100-120 kDa cell surface glycoprotein expressed on T and B cells.
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Réactivité croisée (Details)
- Species reactivity (tested):Human
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Attributs du produit
- Synonyms: Ly-9, T-lymphocyte surface antigen Ly-9, Lymphocyte antigen 9
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Purification
- Protein A affinity chromatography
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Pureté
- > 95 % by SDS-PAGE
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Immunogène
- CD299-transfected 300. 19 pre-B cell line
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Isotype
- IgG1
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Indications d'application
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Flow cytometry: Use peripheral blood lymphocytes as positive control. Immunoprecipitation. Western blot. Immunocytochemistry. Functional Application.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.4
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
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Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer. Avoid repeatedfreezing and thawing.
Shelf life: one year from despatch. -
Date de péremption
- 12 months
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- LY9 (CD229) (Lymphocyte Antigen 9 (CD229))
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Autre désignation
- CD229 / LY9
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Sujet
- CD229 (Ly9) is a cell surface receptor of the CD150 family, which includes also e.g. CD48 and CD224. Receptors of this family regulate cytokine production and cytotoxicity of lymphocytes and NK cells. High levels of CD229 are found on T and B cells, where its expression increases during their maturation. It is absent on granulocytes, bone marrow-derived dendritic cells, platelets and erythrocytes. CD229 has been also reported on mouse monocytes and NK cells. CD229 interacts homophilically through its N-terminal domain and localizes to the contact site between T cells and antigen presenting B cells during antigen-dependent immune synapse formation.Synonyms: Ly-9, Lymphocyte antigen 9, T-lymphocyte surface antigen Ly-9
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ID gène
- 4063
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UniProt
- Q9HBG7
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Pathways
- BCR Signaling
Antigène
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