HAX1 anticorps (N-Term)

N° du produit ABIN492528

Cet anticorps anti-HAX1 est un anticorps Souris Monoclonal détectant HAX1 dans WB et EIA. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour HAX1 anticorps (N-Term) (ABIN492528)

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Reactivité: Humain, Souris, Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp HAX1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: 8F9G7

Détail du produit anti-HAX1 anticorps

Épitope: N-Term

Specificité: This antibody is expected to recognize the longest isoform (Hax1a) as well as the shortest.

Attributs du produit: Synonyms: HAX-1, HS1BP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-bindingprotein 1

Purification: Immunoaffinity Chromotography.

Immunogène: A 15 amino acid peptide near the amino terminus of Human Hax1a (GenBank accession no. NP_006109).

Isotype: IgG

Information d'application

Indications d'application: ELISA. Western Blot: Hax1a antibody can be used for detection of Hax1a at 1-2 μg/mL. Positive Control: Human brain tissue lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.
Shelf life: one year from despatch.

Date de péremption: 12 months

Détails sur HAX1

Antigène: HAX1 (HCLS1 Associated Protein X-1 (HAX1))

Autre désignation: HAX1

Sujet: The HS-1 associated protein X-1 (Hax1) was initially identified in a yeast two-hybrid assay on the basis of its ability to bind to the hemapoietic cell-specific protein 1 (HS-1). Hax1 possesses anti-apoptotic activity and is structurally related to Bcl-2 family members, including the presence of BH1- and BH2-like domains. It has recently been shown to interact with HIV viral protein R (Vpr), a protein required for viral pathogenesis of HIV and linked to T-cell apoptosis through activation of caspases 3 and 9. Other studies indicate that Hax1-mediated processing of HtrA2 (also known as Omi) by the mitochondrial protease PARL allows survival of lymphocytes and neurons when cytokines are limiting. At least four isoforms of Hax1 are known to exist.Synonyms: HAX-1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1, HS1BP1

ID gène: 10456

UniProt: O00165

Pathways: Regulation of Actin Filament Polymerization