CD20 (B Cells) anticorps

N° du produit ABIN4949282

Cet anticorps anti-CD20 (B Cells) est un anticorps Polyclonal produit chez le Lapin, détectant CD20 (B Cells) dans FACS, IF et IHC (p). Convient pour Humain.

Aperçu rapide pour CD20 (B Cells) anticorps (ABIN4949282)

Antigène: CD20 (B Cells)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Inconjugué

Application: Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit

Purification: Protein A affinity chromatography

Immunogène: Recombinant human CD20 protein was used as the immunogen for this CD20 antibody.

Isotype: IgG

Information d'application

Indications d'application: Titering of the CD20 antibody may be required for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 minutes at RT

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: CD20 antibody with azide can be stored at 2-8°C. The azide-free format should be aliquoted and stored at -20°C or colder.

Détail du antigène

Antigène: CD20 (B Cells)

Autre désignation: CD20 (B-cell marker)

Sujet: CD20 is a non-Ig differentiation antigen of B-cells and its expression is restricted to normal and neoplastic B-cells, being absent from all other leukocytes and tissues. CD20 is expressed by pre B-cells and persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood and B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood and lymphoid tissues and their derived lymphomas. In lymphoid tissue, germinal center blasts and B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkin s disease, particularly of lymphocyte predominant type.