Nkx2-2 anticorps
Aperçu rapide pour Nkx2-2 anticorps (ABIN4949366)
Antigène
Voir toutes Nkx2-2 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
-
-
Fonction
- NKX2.2 Antibody (azide and preservative free)
-
Purification
- Protein A affinity chromatography
-
Immunogène
- A human partial recombinant protein was used as the immunogen for this NKX2.2 antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- Titering of the NKX2.2 antibody may be required for optimal performance.
-
Restrictions
- For Research Use only
-
-
-
Format
- Liquid
-
Concentration
- 1 mg/mL
-
Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store the NKX2.2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
-
-
- Nkx2-2 (NK2 Homeobox 2 (Nkx2-2))
-
Autre désignation
- NKX2.2
-
Sujet
- Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. Antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93 % and a specificity of 89 %, and aids in the differential diagnosis of small round cell tumors.
-
UniProt
- O95096
-
Pathways
- Dopaminergic Neurogenesis
Antigène
-