Recombinant PD-1 anticorps

N° du produit ABIN4949389

L’anticorps anti-PD-1 Monoclonal Lapin est utilisé pour la détection de PD-1 dans des échantillons de Humain. Il a été validé pour IHC (p).

Aperçu rapide pour Recombinant PD-1 anticorps (ABIN4949389)

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Type d'anticorp: Recombinant Antibody

Reactivité: Humain

Hôte: Lapin

Clonalité: Monoclonal

Conjugué: Cet anticorp PD-1 est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Classe de qualité: Carrier-free

Clone: PDCD1-1410R

Détail du produit anti-PD-1 anticorps

Fonction: Recombinant PD1 Antibody / Rabbit Monoclonal (azide and preservative free)

Purification: Protein A affinity chromatography

Immunogène: A partial length human protein was used as the immunogen for the recombinant PD1 antibody.

Isotype: IgG, kappa

Information d'application

Indications d'application: Titering of the recombinant PD1 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the recombinant PD1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur PD-1

Antigène: PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

Autre désignation: PD1

Sujet: PDCD1 (Programmed cell death-1 protein), also called PD1 and CD279, is a type I transmembrane receptor and a member of the immunoglobin gene superfamily. It is expressed on activated T-cells, B-cells, and myeloid cells. Anti-PDCD1 is a marker of angioimmunoblastic lymphoma and suggests a unique cell of origin for this neoplasm. Unlike CD10 and BCL6, PDCD1 is expressed by few B-cells, so may be a more specific and useful diagnostic marker in angioimmunoblastic lymphoma.

UniProt: Q15116

Pathways: Cancer Immune Checkpoints